piperylone
- CAS NO.：2531-04-6
- Empirical Formula: C17H23N3O
- Molecular Weight: 285.38
- MDL number: MFCD00864294
- EINECS: 2197884
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-18 19:20:56
What is piperylone?
Originator
Palerol, Novartis
Manufacturing Process
A mixture of 8.8 parts of α-ethylbenzoylacetic acid ethyl ester and 5,3 parts of N-methyl-piperidyl-4-hydrazine is allowed to stand for 30 min at 22°C, after which the mixture is heated for 5 hours to 130°C under a pressure of 12 mm. After 4 hours 1-(N-methylpiperidyl-4)-3-phenyl-4-ethylpyrazolone-5 begins crystallize out. The reaction mixture is allowed to cool, after which the crystal mass is triturated with ether and then recrystallized from methanol-ether or from acetone. Melting point 159-161°C.
Therapeutic Function
Analgesic
Properties of piperylone
| Boiling point: | 413.0±55.0 °C(Predicted) |
| Density | 1.121±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| pka | pK1 5.90; pK2 9.15(at 25℃) |
Safety information for piperylone
Computed Descriptors for piperylone
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