N-(3-AMINOPROPYL) METHACRYLAMIDE
Synonym(s):APMA
- CAS NO.：72607-53-5
- Empirical Formula: C7H15ClN2O
- Molecular Weight: 178.66
- MDL number: MFCD00078257
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 00:00:20
What is N-(3-AMINOPROPYL) METHACRYLAMIDE?
The Uses of N-(3-AMINOPROPYL) METHACRYLAMIDE
APMA can be used in the preparation of copolymers and cross-linked miscellas for gene delivery, drug delivery and diagnostics applications.
General Description
N-(3-Aminopropyl)methacrylamide hydrochloride (APMA) is an aminoalkyl methacrylamide which can be synthesized by adding 1,3-diaminopropane to 1,3-diaminopropane dihydrogen chloride solution and further mixing the solution with methacrylic anhydride and hydroquinone. It has a primary amine that provides attractive features such as pH-responsiveness, affinity for anionic drugs and conjugation for variety of chemical structures.
Properties of N-(3-AMINOPROPYL) METHACRYLAMIDE
| Melting point: | 123-128°C |
| storage temp. | 2-8°C |
| form | powder |
| EPA Substance Registry System | 2-Propenamide, N-(3-aminopropyl)-2-methyl-, monohydrochloride (72607-53-5) |
Safety information for N-(3-AMINOPROPYL) METHACRYLAMIDE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for N-(3-AMINOPROPYL) METHACRYLAMIDE
| InChIKey | XHIRWEVPYCTARV-UHFFFAOYSA-N |
New Products
2-Bromo-4-hydroxypyridine 2-Benzyl-1,1,3,3-tetramethylisoindoline AMINO-O-TOLYL-ACETIC ACID AMINO(2-BROMOPHENYL)ACETIC ACID 6-BROMOTETRAZOLO[1,5-A]PYRIDINE 3-Oxocyclobutanecarboxylic acid 1,3-Diazaspiro[4.5]decane-2,4-dione, 8,8-difluoro- AMINO-(3-FLUORO-PHENYL)-ACETIC ACID Pyrrolo[1,2-a]pyrimidine-6-carboxylic acid, 4,6,7,8-tetrahydro-4-oxo-, sodium salt (1:1), (6S) Obidoxime hydrochloride API Piperazine, 1-(3-methoxyphenyl)-, hydrochloride (1:1) Decanoic acid, 2-[4-(phenylmethoxy)phenyl]ethyl ester 2,4-Dihydroxybenzaldehyde 3-Cyano-4-(2-methylpropoxy)benzenecarbothioamide 1-(2, 4-dichlorophenyl)-N-(2, 4-difluorophenyl)-N isopropyl-5-oxo-1H-1, 2, 4-trizole-4(5H)-carboxamide 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 2-Butyn-1-oL N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine Pirtobrutinib intd. N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamideRelated products of tetrahydrofuran
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