N-(3-AMINOPROPYL) METHACRYLAMIDE
Synonym(s):APMA
- CAS NO.：72607-53-5
- Empirical Formula: C7H15ClN2O
- Molecular Weight: 178.66
- MDL number: MFCD00078257
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:13:56
What is N-(3-AMINOPROPYL) METHACRYLAMIDE?
The Uses of N-(3-AMINOPROPYL) METHACRYLAMIDE
APMA can be used in the preparation of copolymers and cross-linked miscellas for gene delivery, drug delivery and diagnostics applications.
General Description
N-(3-Aminopropyl)methacrylamide hydrochloride (APMA) is an aminoalkyl methacrylamide which can be synthesized by adding 1,3-diaminopropane to 1,3-diaminopropane dihydrogen chloride solution and further mixing the solution with methacrylic anhydride and hydroquinone. It has a primary amine that provides attractive features such as pH-responsiveness, affinity for anionic drugs and conjugation for variety of chemical structures.
Properties of N-(3-AMINOPROPYL) METHACRYLAMIDE
| Melting point: | 123-128°C |
| storage temp. | 2-8°C |
| form | powder |
| EPA Substance Registry System | 2-Propenamide, N-(3-aminopropyl)-2-methyl-, monohydrochloride (72607-53-5) |
Safety information for N-(3-AMINOPROPYL) METHACRYLAMIDE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for N-(3-AMINOPROPYL) METHACRYLAMIDE
| InChIKey | XHIRWEVPYCTARV-UHFFFAOYSA-N |
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