Loxoprofen sodium
- CAS NO.：80382-23-6
- Empirical Formula: C15H19NaO3
- Molecular Weight: 270.3
- MDL number: MFCD00941425
- EINECS: 1806241-263-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 12:01:10
What is Loxoprofen sodium?
Description
Loxoprofen sodium i s an antiinflammatory/analgesic agent useful in the management of rheumatoid arthritis and related disorders. It is converted in vivo to the corresponding trans-hydroxycyclopentane analog, through which it appears to exert its activity.
Originator
Sankyo (Japan)
The Uses of Loxoprofen sodium
anti-inflammatory
Definition
ChEBI: A hydrate that is the dihydrate form of loxoprofen sodium. The parent acid, loxoprofen, is a prodrug that is rapidly converted to its active trans-alcohol metabolite following oral administration.
brand name
LOXONIN
Mechanism of action
As most NSAIDs, loxoprofen is a non-selective cyclooxygenase inhibitor, and works by reducing the synthesis of prostaglandins from arachidonic acid.
Side Effects
Adverse effects include anorexia, nausea, vomiting, bleeding, anemia, diarrhea, and constipation.
Properties of Loxoprofen sodium
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | DMSO: soluble |
| form | A solid |
| color | White to off-white |
| InChI | InChI=1S/C15H18O3.Na.H/c1-10(15(17)18)12-7-5-11(6-8-12)9-13-3-2-4-14(13)16;;/h5-8,10,13H,2-4,9H2,1H3,(H,17,18);; |
| CAS DataBase Reference | 80382-23-6(CAS DataBase Reference) |
Safety information for Loxoprofen sodium
Computed Descriptors for Loxoprofen sodium
| InChIKey | ALZXNWUYLUBHJL-UHFFFAOYSA-N |
| SMILES | C(C1CCCC1=O)C1C=CC(C(C)C(=O)O)=CC=1.[NaH] |
Loxoprofen sodium manufacturer
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