ETHYL 2-METHYL-4,4,4-TRIFLUOROACETOACETATE
- CAS NO.：344-00-3
- Empirical Formula: C7H9F3O3
- Molecular Weight: 198.14
- MDL number: MFCD00190635
- EINECS: 000-000-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 03:21:23
What is ETHYL 2-METHYL-4,4,4-TRIFLUOROACETOACETATE?
The Uses of ETHYL 2-METHYL-4,4,4-TRIFLUOROACETOACETATE
Ethyl 2-(trifluoroacetyl)propionate, can be used in various chemical synthesis such as in the preparation of 5,6-disubstituted thiopyrimidine aryl aminothiazoles as inhibitors of the calcium-activated chloride channel TMEM16A/Ano1.
Properties of ETHYL 2-METHYL-4,4,4-TRIFLUOROACETOACETATE
| Boiling point: | 144 °C |
| Density | 1,2 g/cm3 |
| refractive index | 1.374 |
| Flash point: | 47°C |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly) |
| form | Oil |
| pka | 9.02±0.35(Predicted) |
| color | Colourless to Pale Yellow |
| BRN | 1783620 |
| CAS DataBase Reference | 344-00-3(CAS DataBase Reference) |
Safety information for ETHYL 2-METHYL-4,4,4-TRIFLUOROACETOACETATE
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H226:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for ETHYL 2-METHYL-4,4,4-TRIFLUOROACETOACETATE
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