Trifluoromethanesulfonic acid
Synonym(s):TFMSA;Triflic acid;Triflic acid, TFMS;Trifluoromethanesulfonic acid
- CAS NO.:1493-13-6
- Empirical Formula: CHF3O3S
- Molecular Weight: 150.08
- MDL number: MFCD00007514
- EINECS: 216-087-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-05-20 14:01:34
What is Trifluoromethanesulfonic acid?
The Uses of Trifluoromethanesulfonic acid
Trifluoromethanesulfonic acid acts as a catalyst for esterification reactions and an acidic titrant in nonaqueous acid-base titration. It is useful in protonations due to the presence of conjugate base triflate is non nucleophilic. It serves as a deglycosylation agent for glycoproteins. In addition, it is a precursor and a catalyst in organic chemistry. It reacts with acyl halides to prepare mixed triflate anhydrides, which are strong acylating agents used in Friedel-Crafts reactions. It acts as a key starting material for the preparation of ethers and olefins by reacting with alcohols as well as to prepare trifluoromethanesulfonic anhydride by dehydration reaction.
What are the applications of Application
Trifluoromethanesulfonic acid is a strong monoprotic acid
Properties of Trifluoromethanesulfonic acid
Melting point: | -40 °C |
Boiling point: | 162 °C (lit.) |
Density | 1.696 g/mL at 25 °C (lit.) |
Flash point: | None |
storage temp. | Store below +30°C. |
solubility | Miscible in H<sub>2</sub>O |
form | Fuming Liquid |
appearance | Colorless liquid |
color | slightly brown |
Water Solubility | SOLUBLE |
Sensitive | Hygroscopic |
Safety information for Trifluoromethanesulfonic acid
Signal word | Danger |
Pictogram(s) |
Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H290:Corrosive to Metals H302:Acute toxicity,oral H314:Skin corrosion/irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P234:Keep only in original container. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Trifluoromethanesulfonic acid
InChIKey | ITMCEJHCFYSIIV-UHFFFAOYSA-N |
Abamectin manufacturer
SURVIVAL TECHNOLOGIES LIMITED
Vardhaman P Golechha
AMINO ORGANICS
JSK Chemicals
SRF Limited
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