6-aminotetralin-2,3-diol

Synonym(s):6,7-ADTN hydrobromide

CAS NO.：13575-86-5
Empirical Formula: C10H13NO2
Molecular Weight: 0
MDL number: MFCD00036982
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 03:18:08

What is 6-aminotetralin-2,3-diol?

Description

6,7-ADTN HBr (13575-86-5) is a broad spectrum dopamine receptor agonist.1,2? Demonstrates a marked selectivity for the human dopamine D3 receptor.3 6,7-ADTN and psychostimulants such as cocaine and amphetamine reduce excitatory synaptic transmission in the nucleus accumbens by activating presynaptic dopamine receptors.4

The Uses of 6-aminotetralin-2,3-diol

(+/-)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide is a dopamine receptor agonist in Tribolium castaneum.

What are the applications of Application

6,7-ADTN hydrobromide is a dopamine receptor agonist

References

1) List et al. (1982), Striatal binding of 2-amino-6,7-[3H]dihydroxy-1,2,3,4-tetrahydronaphthalene to two dopaminergic sites distinguished by their low and high affinity for neuroleptics; J. Neurosci., 2 895 2) Templeton et al. (1982), Binding of [3H]ADTN to rat striatal membranes; Biochem. Pharmacol., 31 1629 3) Freedman et al. (1994), Expression and pharmacological characterization of the human D3 dopamine receptor; Curr. J. Pharmacol. Exp. Ther., 268 417 4) Nicola et al. (1996), Psychostimulants depress excitatory synaptic transmission in the nucleus accumbens via presynaptic D1-like dopamine receptors; J. Neurosci., 16 1591

Properties of 6-aminotetralin-2,3-diol

Melting point:	270-271 °C
storage temp.	2-8°C
solubility	Soluble in Water (up to 25 mg/ml)
form	solid
color	Tan
Stability:	Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 1 week.