2-Bromo-1-ethylpyridinium tetrafluoroborate
Synonym(s):BEP
- CAS NO.：878-23-9
- Empirical Formula: C7H9BBrF4N
- Molecular Weight: 273.86
- MDL number: MFCD00060046
- EINECS: 212-900-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 04:54:42
What is 2-Bromo-1-ethylpyridinium tetrafluoroborate?
The Uses of 2-Bromo-1-ethylpyridinium tetrafluoroborate
2-Bromo-1-ethylpyridinium Tetrafluoroborate is a carboxyl activation and coupling reagent for peptide synthesis.
The Uses of 2-Bromo-1-ethylpyridinium tetrafluoroborate
2-Bromo-1-ethyl-pyridinium tetrafluoroborate can be used as a coupling reagent for:
- The synthesis of N-methylated peptides in solution and solid phase.
- The synthesis of cyclosporin A fragment and dolastatin 15 pentapeptide moiety.
General Description
2-Bromo-1-ethyl-pyridinium tetrafluoroborate is a coupling reagent employed in the synthesis of amides and esters through amidation and esterification reactions, respectively. It is generally prepared by the reaction of triethyloxonium tetrafluoroborate with 2?bromo pyridine.
Properties of 2-Bromo-1-ethylpyridinium tetrafluoroborate
| Melting point: | 103-107 °C |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | Crystalline Powder |
| color | White |
| Water Solubility | very faint turbidity |
| BRN | 4059265 |
| CAS DataBase Reference | 878-23-9(CAS DataBase Reference) |
Safety information for 2-Bromo-1-ethylpyridinium tetrafluoroborate
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to..… |
Computed Descriptors for 2-Bromo-1-ethylpyridinium tetrafluoroborate
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