2-Ethylpyridine

CAS NO.：100-71-0
Empirical Formula: C7H9N
Molecular Weight: 107.15
MDL number: MFCD00006361
EINECS: 202-881-9
SAFETY DATA SHEET (SDS)
Update Date: 2025-09-25 17:15:13

What is 2-Ethylpyridine?

Chemical properties

clear colorless to yellowish liquid

The Uses of 2-Ethylpyridine

2-Ethylpyridine is used to study its effect on the proliferation and survival of human umbilical vein endothelial cells (HUVECs), HMVECs from lung, and NIH 3T3 cells. 2-Ethylpyridine linked with silica is a popular stationary phase for chiral and achiral separations in supercritical fluid chromatography.

Synthesis Reference(s)

Tetrahedron Letters, 30, p. 1229, 1989 DOI: 10.1016/S0040-4039(00)72722-5

General Description

2-Ethylpyridine, a nitrogen aromatic compound, is grouped under the class of azaarenes. It is generally found as a component of fuels and combustion products.

Purification Methods

Purify it further by conversion to the picrate, recrystallisation of the picrate and regeneration of the free base followed by distillation. [Beilstein 20/6 V 3.]

Properties of 2-Ethylpyridine

Melting point:	-63°C
Boiling point:	149 °C (lit.)
Density	0.937 g/mL at 25 °C (lit.)
refractive index	n20/D 1.496(lit.)
Flash point:	85 °F
storage temp.	Flammables area
solubility	42g/l
form	clear liquid
pka	5.89(at 25℃)
color	Colorless to Almost colorless
Odor	at 0.01 % in propylene glycol. green grassy
Water Solubility	ca 45 g/L (20 ºC)
BRN	106480
Dielectric constant	8.3300000000000001
CAS DataBase Reference	100-71-0(CAS DataBase Reference)
NIST Chemistry Reference	Pyridine, 2-ethyl-(100-71-0)
EPA Substance Registry System	2-Ethylpyridine (100-71-0)

Safety information for 2-Ethylpyridine

Signal word	Warning
Pictogram(s)	Flame Flammables GHS02 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H226:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.