3-Pyridylboronic acid
Synonym(s):3-Pyridineboronic acid;3-Pyridylboronic acid;Dihydroxy(3-pyridyl)borane;Pyridin-3-ylboronic acid
- CAS NO.：1692-25-7
- Empirical Formula: C5H6BNO2
- Molecular Weight: 122.92
- MDL number: MFCD00674177
- EINECS: 605-544-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:27:05
What is 3-Pyridylboronic acid?
Chemical properties
Light Yellow Powder
The Uses of 3-Pyridylboronic acid
3-Pyridylboronic acid is a reagent used for• ;Phosphine-free Suzuki-Miyaura cross-coupling reactions
1 ;Regioselective Suzuki-Miyaura coupling and tandem palladium-catalyzed intramolecular aminocarbonylation and annulation
2 ;N-arylation using copper acetylacetonate catalyst
3 ;Copper-mediated cyanation and regioselective cyanation of electron-rich benzenes
4 Reagent use in Preparation of • ;New linear poly(phenylpyridyl) chains by Suzuki coupling
5 ;Oligopyridyl foldamers as mimics of a-helix twist
6 ;Many highly significant therapeutic enzymatic and kinase inhibitors and r
The Uses of 3-Pyridylboronic acid
Boronic acid derivatives and their binding affinities with diols.
The Uses of 3-Pyridylboronic acid
suzuki reaction
What are the applications of Application
3-Pyridineboronic Acid is a boronic acid derivatives
Synthesis Reference(s)
The Journal of Organic Chemistry, 64, p. 3846, 1999 DOI: 10.1021/jo9819279
Tetrahedron Letters, 43, p. 4285, 2002
Properties of 3-Pyridylboronic acid
| Melting point: | >300 °C (lit.) |
| Boiling point: | 308.8±34.0 °C(Predicted) |
| Density | 1.22±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Slightly soluble in methanol. |
| form | Powder, Crystals and/or Chunks |
| pka | 4.00±0.10(Predicted) |
| color | White to yellow-orange |
| BRN | 471943 |
| CAS DataBase Reference | 1692-25-7(CAS DataBase Reference) |
Safety information for 3-Pyridylboronic acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 3-Pyridylboronic acid
3-Pyridylboronic acid manufacturer
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product: 1692-25-7 3-Pyridinylboronic acid 98%
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