Pyridine-4-boronic acid

Description

Pyridine-4-boronic acid is a kind of boronic acid derivative. It is useful building blocks in crystal engineering. It can also be used as a catalyst to act as a dehydrative condensation agent to synthesize amides using carboxylic acid and amines as raw materials. Its derivative, polystyrene-bound 4-pyridineboronic acid, is a useful catalyst for amidation reaction and esterification of alpha-hydrocarboxylic acids.

Chemical properties

light orange granular powder

The Uses of Pyridine-4-boronic acid

Boronic acid derivatives and their binding affinities with diols.

The Uses of Pyridine-4-boronic acid

suzuki reaction

The Uses of Pyridine-4-boronic acid

Reagent used for

• Palladium-catalyzed Suzuki-Miyaura coupling reactions
• Ligand-free palladium-catalyzed Suzuki coupling reaction under microwave irradation

• HIV-1 protease inhibitors
• Potential cancer threapeutics, such as PDK1 and protein kinase CK2 inhibitors

What are the applications of Application

4-Pyridineboronic Acid is a boronic acid derivative

References

http://www.wako-chem.co.jp/english/labchem/product/Org/pyridineboronic/
José J. CamposGaxiola et al. "Pyridineboronic Acids as Useful Building Blocks in Combination with Perchloroplatinate(II) and -(IV) Salts: 1D, 2D, and 3D Hydrogen-Bonded Networks Containing X-H•••Cl2Pt− (X = C, N+), B(OH)2•••Cl2Pt−, and B(OH)2•••(HO)2B Synthons." Crystal Growth & Design 10.7(2010).
Kara, H., A. G. Orpen, and T. J. Podesta. "Pyridine boronic acids as building blocks in crystal engineering." Acta Crystallographica 61.Suppl (2001): C357.