2-(Aminomethyl)-1-Boc-piperidine
- CAS NO.：370069-31-1
- Empirical Formula: C11H22N2O2
- Molecular Weight: 214.3
- MDL number: MFCD01317791
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:27:06
What is 2-(Aminomethyl)-1-Boc-piperidine?
Chemical properties
White powder
The Uses of 2-(Aminomethyl)-1-Boc-piperidine
Reactant for synthesis of: TRPV1 antagonists, CHK1 inhibitors, p38a MAP kinase inhibitors, Carbamoylphosphonates, Macrolactams via carbonylation/intramolecular amidation, Intramolecular transamidation.
The Uses of 2-(Aminomethyl)-1-Boc-piperidine
Reactant for synthesis of:
TRPV1 antagonists
CHK1 inhibitors
p38a MAP kinase inhibitors
Carbamoylphosphonates
Macrolactams via carbonylation/intramolecular amidation
Intramolecular transamidation
Reactions
2-(Aminomethyl)-1-Boc-piperidine, also known as Tert-butyl 2-(aminomethyl)piperidine-1-carboxylate, is an important organic reagent that can be used as a building block for the synthesis of many organic compounds, such as tert-butyl 2 - ((2, 6 - dimethyl-phenyl amide) methyl) piperidine -1 - carboxylic esters which can be used for preparing medicines in the fields of local anaesthesia or analgesia.
Properties of 2-(Aminomethyl)-1-Boc-piperidine
| Boiling point: | 299.4±13.0 °C(Predicted) |
| Density | 1.0124 g/mL at 25 °C |
| refractive index | n20/D 1.4745 |
| Flash point: | 110 °C |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | Soluble in DMSO. |
| pka | 10.32±0.29(Predicted) |
| CAS DataBase Reference | 370069-31-1(CAS DataBase Reference) |
Safety information for 2-(Aminomethyl)-1-Boc-piperidine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07  Environment GHS09 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H400:Hazardous to the aquatic environment, acute hazard |
| Precautionary Statement Codes |
P273:Avoid release to the environment. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-(Aminomethyl)-1-Boc-piperidine
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