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HomeProduct name list1-Acetyl-4-piperidinecarboxylic acid

1-Acetyl-4-piperidinecarboxylic acid

Synonym(s):N-Acetylisonipecotic acid

  • CAS NO.:25503-90-6
  • Empirical Formula: C8H13NO3
  • Molecular Weight: 171.19
  • MDL number: MFCD00023706
  • EINECS: 247-049-6
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2025-01-27 09:38:02
1-Acetyl-4-piperidinecarboxylic acid Structural

What is 1-Acetyl-4-piperidinecarboxylic acid?

Chemical properties

White Crystalline Solid

The Uses of 1-Acetyl-4-piperidinecarboxylic acid

A synthetic intermediate in the preparation of CNS depressants

The Uses of 1-Acetyl-4-piperidinecarboxylic acid

Reactant for synthesis of:• ;Triazole derivatives1• ;Antiproliferative agents2• ;CDK inhibitors3• ;CCR5 antagonists for HIV treatment4• ;nhNK1 antagonists5• ;Piperidine derivatives6

The Uses of 1-Acetyl-4-piperidinecarboxylic acid

Metabolite fingerprinting in transgenic Nicotiana tabacum altered by the Escherichia coli glutamate dehydrogenase gene.

What are the applications of Application

1-Acetylisonipecotic Acid is a synthetic intermediate utilized in the preparation of CNS depressants

Properties of 1-Acetyl-4-piperidinecarboxylic acid

Melting point: 180-184 °C (lit.)
Boiling point: 301.17°C (rough estimate)
Density  1.1998 (rough estimate)
refractive index  1.4750 (estimate)
storage temp.  Sealed in dry,Room Temperature
solubility  Methanol (Slightly), Water (Slightly)
form  Crystalline Powder
pka 4.35±0.20(Predicted)
color  White to beige
Water Solubility  50 g/L (20 ºC)
BRN  389577
CAS DataBase Reference 25503-90-6(CAS DataBase Reference)
NIST Chemistry Reference 1-Acetyl-4-piperidinecarboxylic acid(25503-90-6)

Safety information for 1-Acetyl-4-piperidinecarboxylic acid

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H317:Sensitisation, Skin
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 1-Acetyl-4-piperidinecarboxylic acid

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