(+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID
Synonym(s):(±)-3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic acid
- CAS NO.：100828-16-8
- Empirical Formula: C8H17N2O5P
- Molecular Weight: 252.2
- MDL number: MFCD00055136
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 01:24:12
What is (+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID?
The Uses of (+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID
(+)-3-(2-Carboxypiperazin-4-yl)-propyl-1-phosphoric Acid is a compound with NMDA antagonistic activity.
What are the applications of Application
(+)-3-(2-Carboxypiperazin-4-yl)-propyl-1-phosphoric Acid is a compound with NMDA antagonistic activity
Synthesis Reference(s)
Tetrahedron Letters, 30, p. 5193, 1989 DOI: 10.1016/S0040-4039(01)93739-6
Biological Activity
Potent NMDA antagonist. See separate isomer (3-((R)-2-Carboxypiperazin-4-yl)-propyl-1-phosphonicacid ).
Biochem/physiol Actions
Potent and selective NMDA glutamate receptor antagonist; anticonvulsant.
Storage
Room temperature (desiccate)
Properties of (+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID
| Boiling point: | 546.7±60.0 °C(Predicted) |
| Density | 1.408±0.06 g/cm3(Predicted) |
| storage temp. | Desiccate at RT |
| solubility | H2O: 99.2 mg/mL |
| form | solid |
| pka | 1.89±0.20(Predicted) |
| color | white |
| Water Solubility | Soluble to 100 mM in water |
Safety information for (+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID
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![(+/-)-3-(2-CARBOXY-PIPERAZIN-4-YL) PROPYL-1-PHOSPHONIC ACID-[PROPYL-1,2-3H]-](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB1452330.gif)
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