3-Aminopropylphosphonic acid
- CAS NO.：13138-33-5
- Empirical Formula: C3H10NO3P
- Molecular Weight: 139.09
- MDL number: MFCD00008222
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-24 18:13:44
What is 3-Aminopropylphosphonic acid?
Chemical properties
Off-white to faintly greenish powder
The Uses of 3-Aminopropylphosphonic acid
3-Aminopropylphosphonic acid was used as a selective antagonist of GABA(C) receptor.
What are the applications of Application
3-Aminopropylphosphonic acid is a GABAB receptor agonist
Definition
ChEBI: (3-aminopropyl)phosphonic acid is a phosphonic acid in which the hydrogen attached to the phosphorus of phosphonic acid is substituted by a 3-aminopropyl group. It is a partial agonist of GABAB receptors. It has a role as a GABAB receptor agonist. It is a primary amino compound and a member of phosphonic acids. It is functionally related to a phosphonic acid. It is a tautomer of a (3-aminopropyl)phosphonic acid zwitterion.
General Description
The relative nonspecific binding of the DNA-conjugated gold nanoparticles (AuNPs) to the indium-tin oxide electrodes modified with 3-aminopropylphosphonic acid was examined by measuring the electrocatalytic anodic current of hydrazine caused by the nonspecifically absorbed AuNPs.
Biochem/physiol Actions
GABAB receptor agonist; antagonist of basal prolactin secretion.
Properties of 3-Aminopropylphosphonic acid
| Melting point: | 294 °C (dec.)(lit.) |
| Boiling point: | 343.0±44.0 °C(Predicted) |
| Density | 1.378±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMF: 5 mg/ml; DMSO: 2 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml |
| pka | 2.11±0.10(Predicted) |
| form | Powder |
| color | Off-white to faintly greenish |
| Water Solubility | soluble |
Safety information for 3-Aminopropylphosphonic acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 3-Aminopropylphosphonic acid
| InChIKey | GSZQTIFGANBTNF-UHFFFAOYSA-N |
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