3-Aminopropylphosphonic acid

CAS NO.：13138-33-5
Empirical Formula: C3H10NO3P
Molecular Weight: 139.09
MDL number: MFCD00008222
SAFETY DATA SHEET (SDS)
Update Date: 2026-01-13 11:16:46

What is 3-Aminopropylphosphonic acid?

Chemical properties

Off-white to faintly greenish powder

The Uses of 3-Aminopropylphosphonic acid

3-Aminopropylphosphonic acid was used as a selective antagonist of GABA(C) receptor.

What are the applications of Application

3-Aminopropylphosphonic acid is a GABAB receptor agonist

Definition

ChEBI: (3-aminopropyl)phosphonic acid is a phosphonic acid in which the hydrogen attached to the phosphorus of phosphonic acid is substituted by a 3-aminopropyl group. It is a partial agonist of GABAB receptors. It has a role as a GABAB receptor agonist. It is a primary amino compound and a member of phosphonic acids. It is functionally related to a phosphonic acid. It is a tautomer of a (3-aminopropyl)phosphonic acid zwitterion.

General Description

The relative nonspecific binding of the DNA-conjugated gold nanoparticles (AuNPs) to the indium-tin oxide electrodes modified with 3-aminopropylphosphonic acid was examined by measuring the electrocatalytic anodic current of hydrazine caused by the nonspecifically absorbed AuNPs.

Biochem/physiol Actions

GABAB receptor agonist; antagonist of basal prolactin secretion.

Properties of 3-Aminopropylphosphonic acid

Melting point:	294 °C (dec.)(lit.)
Boiling point:	343.0±44.0 °C(Predicted)
Density	1.378±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	DMF: 5 mg/ml; DMSO: 2 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml
pka	2.11±0.10(Predicted)
form	Powder
color	Off-white to faintly greenish
Water Solubility	soluble

Safety information for 3-Aminopropylphosphonic acid

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.