EC 2.6.1.2
Synonym(s):L -Alanine: 2-Oxoglutarate Aminotransferase;Alanine Aminotransferase (catalytic concentration);GPT
- CAS NO.：9000-86-6
- Empirical Formula: C11H16N2O6
- Molecular Weight: 272.25454
- MDL number: MFCD00131192
- EINECS: 232-561-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:58:22
What is EC 2.6.1.2?
The Uses of EC 2.6.1.2
It is used for research and clinical diagnostic assays for liver disease. Alanine transaminase (GPT/ALT) is used in multi-analyte clinical chemistry controls and calibrators for major IVD manufacturers. The alanine aminotransferase (ALT) blood test is typically used to detect liver injury. Some of the other applications include Diagnostic Controls, calibrators & standards, immunoassays, clinical chemistry, testing/assay validation, life Science, manufacturing, validation Studies.
General Description
Glutamic-pyruvic transaminase (GPT) is localized majorly in the liver.
Biochem/physiol Actions
Glutamic-pyruvic transaminase (GPT) mediates the transfer of the amino group to α-ketoglutarate from l-alanine. It plays a key role in gluconeogenesis and amino acid metabolism. The role of GPT in various kinds of tumors has been reported.
Properties of EC 2.6.1.2
| storage temp. | -70°C |
| form | suspension (aqueous) |
| color | green-yellow |
| Water Solubility | Dissolves readily at 5 mg/ml in 0.05M potassium phosphate pH 7.5 to give a clear, pale-green solution. Soluble in distilled water or dilute buffer. |
| BRN | 3562140 |
| EPA Substance Registry System | Aminotransferase, alanine (9000-86-6) |
Safety information for EC 2.6.1.2
| Signal word | Danger |
| Pictogram(s) |
 Health Hazard GHS08 |
| GHS Hazard Statements |
H334:Sensitisation, respiratory |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P284:Wear respiratory protection. P501:Dispose of contents/container to..… |
Computed Descriptors for EC 2.6.1.2
New Products
2-(2-Ethoxyphenoxy)ethyl bromide 1,3-Dibromo-2,2-dimethoxypropane 8-Bromo-7-(2-butynyl)-3-methyl xanthine 5-Chlorothiophene-2-carboxylic acid 8-Bromo-3-methyl xanthine Maleic hydrazide o-Anisaldehyde 4-Bromobenzaldehyde 3-Fluorobenzaldehyde 2-Chlorobenzaldehyde 3-Amino-3-(3-fluorophenyl)propanoic acid 1-Propyl-4-piperidone 2,3-Dihydro-5,6-dimethoxy-2-(4-piperidinylmethyl)-1H-inden-1-one hydrochloride 3-(4-Bromo-3-methyl-2-oxo-2,3-dihydro-1h-benzo[d]imidazol-1-yl)piperidine-2,6-dione 2-Fluoro-6-iodobenzoic acid 3-Pyridineacrylic acid 1-Boc-4-cyanopiperidine ethyl 2-oxo-2,3,9,10-tetrahydro-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxaline-8(7H)-carboxylate Vardenafil Bis-sulphonamide(Dimer) Nitroso Irbesartan N-Nitroso Nortriptyline Sulfonic acid Impurity 2-(p-Tolyl)acetaldehyde 2,2-dibromo-1-cyclopropyl-2-(2-fluorophenyl)ethan-1-oneRelated products of tetrahydrofuran
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