METHYL ISOCYANOACETATE
- CAS NO.：39687-95-1
- Empirical Formula: C4H5NO2
- Molecular Weight: 99.09
- MDL number: MFCD00000006
- EINECS: 254-593-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:13:24
What is METHYL ISOCYANOACETATE?
Chemical properties
CLEAR YELLOW TO BROWN LIQUID
The Uses of METHYL ISOCYANOACETATE
Methyl isocyanoacetate is used in the copper-catalyzed, diastereoselective synthesis of oxazolines. It is involved in the direct aldol reaction with carbonyl compounds to prepare corresponding oxazoline by using catechol-copper network catalyst. Further, it is also involved in four-component Ugi condensation reaction. It undergoes asymmetric aldol reaction with fluorinated benzaldehyde using gold(I) as a catalyst.
The Uses of METHYL ISOCYANOACETATE
Methyl isocyanoacetate has been used in the copper-catalyzed, diastereoselective synthesis of oxazolines.
General Description
Methyl isocyanoacetate undergoes direct aldol reaction with carbonyl compounds in the presence of solid-phase catechol-copper network catalyst to yield corresponding oxazolines. It also participates in four-component Ugi condensation reaction.
Properties of METHYL ISOCYANOACETATE
| Boiling point: | 75-76 °C10 mm Hg(lit.) |
| Density | 1.09 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 193 °F |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
| form | Liquid |
| color | Clear yellow to brown |
| Water Solubility | Miscible with organic solvents. Slightly miscible with water. |
| BRN | 3537963 |
| CAS DataBase Reference | 39687-95-1(CAS DataBase Reference) |
Safety information for METHYL ISOCYANOACETATE
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for METHYL ISOCYANOACETATE
METHYL ISOCYANOACETATE manufacturer
Ina pharmaceuticals Pvt Ltd
3Y
Phone:+91-7815933367
Whatsapp: +91-78159 33367
product: 39687-95-1 99%
ALS India Life Sciences Pvt. Ltd
3Y
Phone:+91-8977036378
Whatsapp: +91 8008166674
product: 39687-95-1 Methyl isocyanoacetate 95.00%
New Products
2-(2-Ethoxyphenoxy)ethyl bromide 1,3-Dibromo-2,2-dimethoxypropane 8-Bromo-7-(2-butynyl)-3-methyl xanthine 5-Chlorothiophene-2-carboxylic acid 8-Bromo-3-methyl xanthine Maleic hydrazide o-Anisaldehyde 4-Bromobenzaldehyde 3-Fluorobenzaldehyde 2-Chlorobenzaldehyde 3-Amino-3-(3-fluorophenyl)propanoic acid 1-Propyl-4-piperidone 2,3-Dihydro-5,6-dimethoxy-2-(4-piperidinylmethyl)-1H-inden-1-one hydrochloride 3-(4-Bromo-3-methyl-2-oxo-2,3-dihydro-1h-benzo[d]imidazol-1-yl)piperidine-2,6-dione 2-Fluoro-6-iodobenzoic acid 3-Pyridineacrylic acid 1-Boc-4-cyanopiperidine ethyl 2-oxo-2,3,9,10-tetrahydro-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxaline-8(7H)-carboxylate Vardenafil Bis-sulphonamide(Dimer) Nitroso Irbesartan N-Nitroso Nortriptyline Sulfonic acid Impurity 2-(p-Tolyl)acetaldehyde 2,2-dibromo-1-cyclopropyl-2-(2-fluorophenyl)ethan-1-oneRelated products of tetrahydrofuran
You may like
-
Methyl 2-isocyanoacetate 39687-95-1 99%View Details
39687-95-1 -
39687-95-1 Methyl isocyanoacetate 98%View Details
39687-95-1 -
Methyl Isocyanoacetate CAS 39687-95-1View Details
39687-95-1 -
METHYL-2-ISOCYANOACETATE 96% CAS 39687-95-1View Details
39687-95-1 -
Methyl 2-isocyanoacetate CAS 39687-95-1View Details
39687-95-1 -
Methyl isocyanoacetate CAS 39687-95-1View Details
39687-95-1 -
39687-95-1 Methyl isocyanoacetate 95.00%View Details
39687-95-1 -
39687-95-1 99%View Details
39687-95-1
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.