3-Aminopyridine
Synonym(s):3-Pyridinamine
- CAS NO.:462-08-8
- Empirical Formula: C5H6N2
- Molecular Weight: 94.11
- MDL number: MFCD00006400
- EINECS: 207-322-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 02:07:29
What is 3-Aminopyridine?
Chemical properties
white to light yellow crystal powder
The Uses of 3-Aminopyridine
manufacture of pharmaceuticals and dyes.
The Uses of 3-Aminopyridine
3-Aminopyridine is a monosubstituted pyridine that shows convulsive effects on cortical Neurons. 3-Aminopyridine is used in the synthesis of of organic ligand 3-Pyridylnicotinamide. 3-Aminopyridine al ong with other aminopyridines have been shown to reversibly block voltage-dependent potassium channels,
The Uses of 3-Aminopyridine
3-Aminopyrodine is also used as an intermediate for agrochemicals, pharmaceuticals and colorants. These are involved in photosensitizer chemistry, luminescent materials, metal complex chemistry and liquid crystal. Aminopyridine is used as a monomer for polymerization. It is also used in the Production of cationic dyes and Apa amoxicillin sodium raw materials.
Synthesis Reference(s)
Tetrahedron Letters, 39, p. 1313, 1998 DOI: 10.1016/S0040-4039(97)10877-2
The Journal of Organic Chemistry, 57, p. 5254, 1992 DOI: 10.1021/jo00045a047
Safety Profile
Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. When heated to decomposition it emits toxic fumes of NOx,.
Purification Methods
It crystallises from *benzene, CHCl3/pet ether (b 60-70o), or *benzene/pet ether (4:1). [Beilstein 22/9 V 3.]
Properties of 3-Aminopyridine
| Melting point: | 60-63 °C(lit.) |
| Boiling point: | 248 °C(lit.) |
| Density | 1.0308 (estimate) |
| refractive index | 1.5560 (estimate) |
| Flash point: | 124 °C |
| storage temp. | Poison room |
| solubility | >1000g/l |
| form | Liquid |
| pka | 6.04(at 25℃) |
| color | Clear colorless to yellow |
| PH | 10 (100g/l, H2O, 20℃) |
| Water Solubility | It is soluble in water as well as soluble in alcohol, benzene. |
| Sensitive | Air Sensitive & Hygroscopic |
| Merck | 14,473 |
| BRN | 105692 |
| CAS DataBase Reference | 462-08-8(CAS DataBase Reference) |
| NIST Chemistry Reference | 3-Pyridinamine(462-08-8) |
| EPA Substance Registry System | 3-Aminopyridine (462-08-8) |
Safety information for 3-Aminopyridine
| Signal word | Danger |
| Pictogram(s) |
![]() Skull and Crossbones Acute Toxicity GHS06 ![]() Health Hazard GHS08 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H373:Specific target organ toxicity, repeated exposure |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P314:Get medical advice/attention if you feel unwell. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 3-Aminopyridine
| InChIKey | CUYKNJBYIJFRCU-UHFFFAOYSA-N |
3-Aminopyridine manufacturer
Ina pharmaceuticals Pvt Ltd
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