Z-Vad-fmk, non-methylated
Synonym(s):Caspase Inhibitor VI - CAS 161401-82-7 - Calbiochem;Z-VAD-FMK
- CAS NO.：161401-82-7
- Empirical Formula: C21H28FN3O7
- Molecular Weight: 453.46
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-03-13 23:13:44
What is Z-Vad-fmk, non-methylated?
Description
Z-
General Description
An irreversible general caspase inhibitor. Useful for studies involving recombinant, isolated, and purified caspase enzymes. Unlike Caspase Inhibitor I (Cat. No. 627610), this inhibitor does not require pretreatment with esterase for in vitro studies. A 10 mM (1 mg/221 μl) solution of Caspase Inhibitor VI (Cat. No. 219011) in DMSO is also available.
Biochem/physiol Actions
Product does not compete with ATP.
Properties of Z-Vad-fmk, non-methylated
| Boiling point: | 758.0±60.0 °C(Predicted) |
| Density | 1.260±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMSO:5.0(Max Conc. mg/mL);11.0(Max Conc. mM) |
| form | Off-white solid |
| pka | 3.91±0.19(Predicted) |
| color | White to light yellow |
Safety information for Z-Vad-fmk, non-methylated
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Z-Vad-fmk, non-methylated
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