Z-PHE-DL-ALA-FLUOROMETHYLKETONE

Description

Z-FA-FMK is an irreversible inhibitor of cysteine proteases, including cathepsins B, L, and S, cruzain, and papain. It also inhibits effector caspases-2, -3, -6, and -7 (IC₅₀ = 6-32 μM) without affecting the initiator caspases-8 and -10. Z-FA-FMK also modulates infection by certain bacteria, parasites, and viruses. It can be used both in cells and in vivo.

The Uses of Z-PHE-DL-ALA-FLUOROMETHYLKETONE

Z-FA-FMK is an irreversible cysteine protease inhibitor. It also inhibits papain and cruzain.

What are the applications of Application

Z-FA-FMK is inhibits effector, but not initator caspases in vitro, and suppress some forms of apoptosis