TIQ-A
- CAS NO.：420849-22-5
- Empirical Formula: C11H7NOS
- Molecular Weight: 201.24
- MDL number: MFCD06407947
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-04-17 18:22:24
What is TIQ-A?
Chemical properties
Dark Brown Solid
The Uses of TIQ-A
A cell permeable, potent PARP inhibitor with an IC50 of 450nM. Shown to be neuroprotective against oxygen-glucose deprivation injury in vitro in cultured murine cortical cells ( IC50 of 150nM) and i n vivi in rat transient focal ischemia model (3 mg/kg ip).
The Uses of TIQ-A
A cell permeable, potent PARP inhibitor with an IC50 of 450nM. Shown to be neuroprotective against oxygen-glucose deprivation injury in vitro in cultured murine cortical cells ( IC50 of 150nM) and in vivi in rat transient focal ischemia model (3 mg/kg ip).
What are the applications of Application
TIQ-A is an inhibitor of poly(ADP-ribose) polyerase-1 (PARP-1)
Properties of TIQ-A
| Melting point: | 256-258°C |
| Boiling point: | 282.2±9.0 °C(Predicted) |
| Density | 1.358±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: 16 mg/mL, soluble |
| pka | 13.04±0.20(Predicted) |
| form | solid |
| color | Light green to green |
Safety information for TIQ-A
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H312:Acute toxicity,dermal H332:Acute toxicity,inhalation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for TIQ-A
New Products
N,O-Dimethylhydroxylamine hydrochloride DL-beta-(3-Bromophenyl)alanine N,N CARBONYL DIIMIDAZOLE 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid (R)-1-Benzyl-3-pyrrolidinecarbonitrile Bupropian related compound F Lantanoprost rc B Clidinium Bromide Impurity Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity N-Nitroso hydroxy Cetrizine EP Impurity-A 2,2'-(5-methyl-1,3-phenylene)-di(2-Methylpropionitrile) 1-methyl amino-2,4-dinitro benzene 5-Methyl-1,3-benzenediacetonitrile 4-Fluorothiophenol (R)-BoroLeu-(+)-Pinanediol-CF3COOH 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 2-Chloro Benzylcyanide 3-chlorobenzyl cyanide 3,4 Diethoxy Benzylcyanide 3,4 Dimethoxy Benzylcyanide 3-Hydroxypropionitrile 4-Bromo BenzylcyanideRelated products of tetrahydrofuran
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