Sophoramine
- CAS NO.：6882-66-2
- Empirical Formula: C15H20N2O
- Molecular Weight: 244.33
- MDL number: MFCD01632128
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-07-12 16:50:55
What is Sophoramine?
Description
An alkaloid present in Sophora alopecuroides, the base possesses the tetracyclic structure characteristic of the Sophora alkaloids. It is 1aevorotatory with [α]D - 90.85° or - 98° (EtOH). It yields a series of well crystalline salts and derivatives including the hydrochloride, m.p. 247-8° (dec.); hydriodide, m.p. 294-6°C; aurichloride, m.p. 183-4°C (dec.); p1atinich1oride, m.p. 245-7°C (dec.); picrate, m.p. 229-231°C (dec.) and the picrolonate, m.p. 173-5°C (dec.).
The Uses of Sophoramine
Sophoramine is a quinolizidine alkaloid isolated from traditional Chinese herbal drugssuch as Sophora flavescens Ait. (Kushen), S. alopecuroides L. (Kudouzi or Kugancao) and S. tonkinensis Gapnep (Shandougen).
Definition
ChEBI: Sophoramine is a naphthyridine derivative.
References
Orekhov., Chern. Zentr., II, 2215 (1935)
Orekhov, Proskurnina, Konovalova., Ber., 68,431 (1935)
Proskurnina, Kuzovkov., Dokl. Akad. Nauk SSSR, 91, 1145 (1953)
Okuda et al., Chern. & Ind., 1326 (1962)
Properties of Sophoramine
| Melting point: | 164-5°C |
| Boiling point: | 455.6±34.0 °C(Predicted) |
| Density | 1.22±0.1 g/cm3(Predicted) |
| pka | 9.67±0.20(Predicted) |
| NIST Chemistry Reference | Sophoramine(6882-66-2) |
Safety information for Sophoramine
Computed Descriptors for Sophoramine
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