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HomeProduct name listMatrine

Matrine

Synonym(s):Matridin-15-one;Sophocarpidine

  • CAS NO.:519-02-8
  • Empirical Formula: C15H24N2O
  • Molecular Weight: 248.36
  • MDL number: MFCD00210527
  • EINECS: 610-750-6
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-06-11 18:14:38
Matrine Structural

What is Matrine?

Description

Matrine is extracted by organic solvents from the dry roots, plants, and fruits of kushen 苦参 (Sophora flavescens Ait) and also existed in S. alopecuroides L. and S. subprostrata Chun et T.?Chen.
Chinese medicine Radix sophorae flavescentis have dampness eliminating insecticide and diuretic effects. Sophora flavescens is used for heat dysentery, hemafecia, jaundice and anuria, red leukorrhea, vulva pruritus, eczema, wet sores, skin itching, scabies, ringworm, and trichomonas vaginitis. Sophora flavescens is recorded in the ancient Materia Medica. “Southern Yunnan Materia Medica” also recorded the effects of Saphora flavescens .
Sophora flavescens is a species of Sophora japonica and distributed in temperate and subtropical regions. Sophora flavescens is widely distributed in China, mainly in the north of Hebei, the west of Henan, and southwest of Shandong, Anhui, Hubei, and Guizhou. Matrine is extracted and isolated from the Chinese medicine Sophora flavescens

The Uses of Matrine

(+)-Matrine is an alkaloid compound extracted from the roots of Sophora species which maintain anti-inflammatory, anti-cancer and a host of other positive pharmacological effects. Apoptotic agent.

What are the applications of Application

Matrine is an alkaloid that displays κ-opioid receptor agonism

Properties of Matrine

Melting point: 77 C
Boiling point: 86-88C/2,5Torr
Density  1,191g/cm
storage temp.  Sealed in dry,2-8°C
solubility  Soluble in Water (up to 25 mg/ml)
form  solid
color  White

Safety information for Matrine

Signal word Warning
Pictogram(s)

Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
Precautionary Statement Codes P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501:Dispose of contents/container to..…

Computed Descriptors for Matrine

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