Sophocarpine Monohydrate
- CAS NO.：145572-44-7
- Empirical Formula: C15H22N2O
- Molecular Weight: 246.35
- MDL number: MFCD27923119
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-03-13 23:13:44
What is Sophocarpine Monohydrate?
Description
A tetracyclic alkaloid present in Sophora species, this base crystallizes from H20 as the monohydrate, m.p. 54-5°C which becomes anhydrous in vacuo. It has [α]18D - 29.44° (EtOH) and yields the following salts: hydrochloride, m.p. > 300°C; hydriodide, m.p. 277-9°C; aurichloride, m.p. l66-7°C; platinichloride, m.p. 207-212°C (dec.); picrate, m.p. ISS-7°C and the methiodide, m.p. 200-2°C. Reduction of the base by electrolysis yields a crystalline, volatile base, ClsH26N2, b.p. l53-4°C/5 mm; [α]D - 26.2° (EtOH) and giving a methiodide with a melting point above 300°C. Attempted degradation by the Hofmann process has proved unsuccessful.
The Uses of Sophocarpine Monohydrate
Sophocarpine Monohydrate alleviates non-alcoholic steatohepatitis, which is a resultant effect of non-alcoholic fatty lifer disease. Admission of this compound results in a decrease in liver weight and serum lipids. Antiviral agent, Sophocarpine also displays a profound effect against coxsackievirus and therapeutical effects of viral myocarditis.
References
Orekhov, Proskurnina., Ber., 67,77 (1934)
Proskurnina, Kuzuvkov., Dokl. Akad. Nauk SSSR, 91, 1145 (1953)
Okuda et al., Chern. & Ind., 1326 (1962)
Properties of Sophocarpine Monohydrate
| Melting point: | 8l-2°C |
| storage temp. | -20°C Freezer |
| solubility | Acetone; Dichloromethane |
| form | Solid |
| color | Pale brownish |
Safety information for Sophocarpine Monohydrate
Computed Descriptors for Sophocarpine Monohydrate
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