(R)-(+)-4-CHLOROMETHYL-2,2-DIMETHYL-1,3-DIOXOLANE
- CAS NO.:57044-24-3
- Empirical Formula: C6H11ClO2
- Molecular Weight: 150.6
- MDL number: MFCD00273371
- EINECS: 629-411-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:26:53
What is (R)-(+)-4-CHLOROMETHYL-2,2-DIMETHYL-1,3-DIOXOLANE?
Chemical properties
Clear colorless to yellow liquid
The Uses of (R)-(+)-4-CHLOROMETHYL-2,2-DIMETHYL-1,3-DIOXOLANE
(R)-4-Chloromethyl-2,2-dimethyl-1,3-dioxolane is often used in biosynthetic preparations.
The Uses of (R)-(+)-4-CHLOROMETHYL-2,2-DIMETHYL-1,3-DIOXOLANE
Utilized in the preparation of both enantiomers of the orally active antifungal azolic agent ketoconazole.
Properties of (R)-(+)-4-CHLOROMETHYL-2,2-DIMETHYL-1,3-DIOXOLANE
| Boiling point: | 63 °C37 mm Hg(lit.) |
| alpha | 42.1 º (NEAT) |
| Density | 1.103 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 123 °F |
| form | clear liquid |
| color | Colorless to Almost colorless |
| optical activity | [α]24/D +42.1°, neat |
| BRN | 4654188 |
| CAS DataBase Reference | 57044-24-3(CAS DataBase Reference) |
Safety information for (R)-(+)-4-CHLOROMETHYL-2,2-DIMETHYL-1,3-DIOXOLANE
| Signal word | Danger |
| Pictogram(s) |
![]() Flame Flammables GHS02 ![]() Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H226:Flammable liquids H318:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (R)-(+)-4-CHLOROMETHYL-2,2-DIMETHYL-1,3-DIOXOLANE
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