4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE
- CAS NO.：4362-40-7
- Empirical Formula: C6H11ClO2
- Molecular Weight: 150.6
- MDL number: MFCD00046097
- EINECS: 224-452-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:59:00
What is 4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE?
Chemical properties
clear colourless to light yellow liquid
The Uses of 4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE
4-Chloromethyl-2,2-dimethyl-1,3-dioxolane is used in biosynthetic preparations.
The Uses of 4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE
4-Chloromethyl-2,2-dimethyl-1,3-dioxolane may be used in the preparation of 2,2-dimethyl-4-methylene-1,3-dioxolane via dehydrochlorination.
Synthesis Reference(s)
Canadian Journal of Chemistry, 44, p. 1331, 1966 DOI: 10.1139/v66-199
General Description
4-Chloromethyl-2,2-dimethyl-1,3-dioxolane is a ketal that can be synthesized by the reaction of 3-chloro-propane-1,2-diol (3-MCPD) with acetone in the presence of p-toluene sulfonic acid.
Properties of 4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE
| Boiling point: | 156-158 °C(lit.) |
| Density | 1.063 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 128 °F |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Oil |
| color | Colourless |
| Stability: | Volatile |
| CAS DataBase Reference | 4362-40-7 |
| EPA Substance Registry System | 1,3-Dioxolane, 4-(chloromethyl)-2,2-dimethyl- (4362-40-7) |
Safety information for 4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H226:Flammable liquids H301:Acute toxicity,oral |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. |
Computed Descriptors for 4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE
New Products
Hendecanoic acid 2-Amino-5-cyanopyridine 2-Bromo-5-cyanopyridine DL-3-Amino-3-(2-methoxyphenyl)propionic acid 3-Hydroxypropionitrile 2-AMINO-3-METHYLQUINOLINE HYDROCHLORIDE 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 5-Amino-3-(trifluoromethyl)picolinonitrile 4,6-Dichloro-3-methylpyridazine 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline Trenbolone acetate 3-Methylamino-1,2-propanediol 4-Bromobenzaldehyde 2-Amino-4-phenyl-thiazole 4-Chloro-2-methyl quinoline 2-(Chloromethyl) quinazolin-4(3H)-one 5-Phenyl-[1,3,4]-thiadiazol-2-amine 2-Chloro-6-nitro benzothiazole 1-(3-Hydroxyphenyl)-2-thiourea 3-methyl-8-(trifluoromethyl)quinolin-4-ol N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methacrylamide 1-(4-Aminopiperidin-1-yl)-3,3,3-trifluoropropan-1-one 5-chloro-2-(4-methoxybenzyl)-4-(trifluoromethyl)pyridazin-3(2H)-one 3-cyanocyclohexane-1-carboxylic acidRelated products of tetrahydrofuran
![2-(CHLOROMETHYL)-1,4-DIOXASPIRO[4.4]NONANE](https://img.chemicalbook.in/StructureFile/ChemBookStructure5/GIF/CB3463541.gif)
![2-(CHLOROMETHYL)-1,4-DIOXASPIRO[4.11]HEXADECANE](https://img.chemicalbook.in/StructureFile/ChemBookStructure3/GIF/CB0379339.gif)
![4-CHLOROMETHYL-2-ISOBUTYL-2-METHYL-[1,3]DIOXOLANE](https://img.chemicalbook.in/StructureFile/ChemBookStructure5/GIF/CB3218992.gif)
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