(R)-(+)-Tetrahydro-2-furoic acid
- CAS NO.：87392-05-0
- Empirical Formula: C5H8O3
- Molecular Weight: 116.12
- MDL number: MFCD00211271
- EINECS: 627-523-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:59:05
What is (R)-(+)-Tetrahydro-2-furoic acid?
Description
(R)-(+)-2-Tetrahydrofuroic acid is an important pharmaceutical intermediate compound used in the preparation of β-lactam antibiotics (Faropenem sodium), influenza antiviral drugs (Baloxavir Marboxil), hypertension drugs (Terazosin), and anticancer drugs.
Chemical properties
Colorless to light yellow liquid
The Uses of (R)-(+)-Tetrahydro-2-furoic acid
(R)-(+)-2-Tetrahydrofuroic acid is a heterocyclic derivative and can be used as a pharmaceutical intermediate.
Properties of (R)-(+)-Tetrahydro-2-furoic acid
| Boiling point: | 128-129 °C13 mm Hg(lit.) |
| alpha | +19.6±0.2°(neat) (D/20℃) |
| Density | 1.209 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | >230 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | clear liquid |
| pka | 3.60±0.20(Predicted) |
| color | Colorless to Light yellow |
| optical activity | [α]23/D +4°, c = 1 in methanol |
| BRN | 4658739 |
| CAS DataBase Reference | 87392-05-0(CAS DataBase Reference) |
Safety information for (R)-(+)-Tetrahydro-2-furoic acid
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (R)-(+)-Tetrahydro-2-furoic acid
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