2-Tetrahydrofuroic acid
Synonym(s):Tetrahydrofuran-2-carboxylic acid
- CAS NO.：16874-33-2
- Empirical Formula: C5H8O3
- Molecular Weight: 116.12
- MDL number: MFCD00022473
- EINECS: 605-530-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:58:15
What is 2-Tetrahydrofuroic acid?
Chemical properties
Colorless to light yellow liqui
The Uses of 2-Tetrahydrofuroic acid
2-Tetrahydrofuroic acid is used as a reagent to synthesize Alfuzosin (HCl: A532000), an unselective alpha-1 blocker that is used to treat lower urinary tract symptoms and benign prostatic hyperplasia.
What are the applications of Application
Tetrahydro-2-furoic acid is a specific PRODH (proline dehydrogenase) inhibitor
General Description
Tetrahydro-2-furoic acid inhibits the programmed cell death of Xanthomonas campestris strains. It is a specific inhibitor of proline dehydrogenase, a mitochondrial flavoenzyme that oxidizes proline.
Properties of 2-Tetrahydrofuroic acid
| Melting point: | 21°C |
| Boiling point: | 128-129 °C13 mm Hg(lit.) |
| Density | 1.209 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 139 °C |
| storage temp. | Sealed in dry,2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 3.60±0.20(Predicted) |
| form | Liquid |
| color | Clear yellow to brown |
| Water Solubility | soluble |
| BRN | 109671 |
| CAS DataBase Reference | 16874-33-2(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Furancarboxylic acid, tetrahydro-(16874-33-2) |
| EPA Substance Registry System | 2-Furancarboxylic acid, tetrahydro- (16874-33-2) |
Safety information for 2-Tetrahydrofuroic acid
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Tetrahydrofuroic acid
New Products
2-(2-Ethoxyphenoxy)ethyl bromide 1,3-Dibromo-2,2-dimethoxypropane 8-Bromo-7-(2-butynyl)-3-methyl xanthine 5-Chlorothiophene-2-carboxylic acid 8-Bromo-3-methyl xanthine Maleic hydrazide 4-Bromobenzaldehyde 3-Bromobenzaldehyde 2-Chlorobenzaldehyde 3-Fluorobenzaldehyde 3-Amino-3-(3-fluorophenyl)propanoic acid 1-Propyl-4-piperidone 2,3-Dihydro-5,6-dimethoxy-2-(4-piperidinylmethyl)-1H-inden-1-one hydrochloride 2-Fluoro-6-iodobenzoic acid 3-(4-Bromo-3-methyl-2-oxo-2,3-dihydro-1h-benzo[d]imidazol-1-yl)piperidine-2,6-dione 1-Boc-4-cyanopiperidine 3-Pyridineacrylic acid ethyl 2-oxo-2,3,9,10-tetrahydro-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxaline-8(7H)-carboxylate N-Nitroso Nortriptyline Vardenafil Bis-sulphonamide(Dimer) 1-nitro-3,5-dimethyl adamantine (NMEM) Nabumetone Impurity 5 3-(2-aminoethyl) benzene sulfonamide 2,2-dibromo-1-cyclopropyl-2-(2-fluorophenyl)ethan-1-oneRelated products of tetrahydrofuran
![2,2'-(1,4-Piperazinediyl)bis[6,7-diMethoxy-4-quinazolinaMine]](https://img.chemicalbook.in/CAS/GIF/102839-00-9.gif)
![1-[4-(4-AMino-6,7-diMethoxy-2-quinazolinyl)-1-piperazinyl]-5-hydroxy-1-pentanone](https://img.chemicalbook.in/CAS/GIF/109678-71-9.gif)
Methanone](https://img.chemicalbook.in/CAS/GIF/105356-90-9.gif)
You may like
-
Tetrahydro-2-furancarboxylic acid 99%View Details -
16874-33-2 98%View Details
16874-33-2 -
Tetrahydrofuran-2-carboxylic Acid CAS 16874-33-2View Details
16874-33-2 -
(S)-2-Bromobutanoic acid 32659-49-7 97-99%View Details
32659-49-7 -
ethyl 1-(2,4-dichlorophenyl)-4,5-dihydro-1H-benzo[g]indazole-3-carboxylate 97-99%View Details
665020-24-6 -
1872090-65-7 Methyl 1-(2,2,2-trifluoroethyl)azetidine-3-carboxylate 97-99%View Details
1872090-65-7 -
6-Chloro-3,4-dimethylpyridin-2-amine 1503408-77-2 97-99%View Details
1503408-77-2 -
1-(3,5-dichlorophenyl)-2,2,2-trifluoroethan-1-ol 1187989-89-4 97-99%View Details
1187989-89-4
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.