Pyrophosphatase
Synonym(s):Inorganic Pyrophosphatase;Pyrophosphate phosphohydrolase
- CAS NO.：9024-82-2
- Empirical Formula: NULL
- Molecular Weight: 0
- MDL number: MFCD00131379
- EINECS: 232-784-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 02:58:00
What is Pyrophosphatase?
The Uses of Pyrophosphatase
Inorganic pyrophosphatase (PPase) is a ubiquitous enzyme catalyzing the reaction PPi + H2O → 2Pi.
It plays an important role in protein, RNA, and DNA synthesis.
Definition
An inorganic pyrophos- phatase.
General Description
Pyrophosphatase from E coli (E-PPase) has a broader pH optimum and contains four divalent cations per subunit. It comprises 175 amino acids with additional aspartate residue in the active site cavity. Structurally E-PPase is a homohexamer with six identical 20 kDa subunits. Magnesium is a cofactor for E-PPase.
Biochem/physiol Actions
Pyrophosphatase from E coli (E-PPase) is an essential enzyme in yeast and bacteria The active site residues are crucial for binding to magnesium.
Properties of Pyrophosphatase
| storage temp. | -20°C |
| form | powder |
| color | off-white |
Safety information for Pyrophosphatase
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Pyrophosphatase
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