Pyrithione
- CAS NO.：1121-30-8
- Empirical Formula: C5H5NOS
- Molecular Weight: 127.16
- MDL number: MFCD00059791
- EINECS: 214-328-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-22 18:57:36
What is Pyrithione?
Description
The sodium salt of N-hydroxy-2-pyridinethiones has a germicidal activity againts yeasts and fungi. Sodium omadine is a 40% aqueous solution of sodium pyrithione.
The Uses of Pyrithione
It is used in the metallurgical industry as a component of water-based metalwork fluids, of aceto-polyvinyl lattices, water-based printer's ink, lubrieant for synthetie fibers and anti-dandruff shampoos. A case was reported in a metallurgie worker.
Definition
ChEBI: A pyridinethione that is pyridine-2(1H)-thione in which the hydrogen attached to the nitrogen is replaced by a hydroxy group. It is a Zn2+ ionophore; the zinc salt is used as an antifungal and antibacterial agent.
Synthesis Reference(s)
Journal of the American Chemical Society, 72, p. 4362, 1950 DOI: 10.1021/ja01166a008
Properties of Pyrithione
| Melting point: | 68°C |
| Boiling point: | 253.8±23.0 °C(Predicted) |
| Density | 1.255 (estimate) |
| refractive index | 1.5480 (estimate) |
| storage temp. | 2-8°C |
| solubility | DMSO: 125 mg/mL (983.01 mM) |
| pka | 4.70±0.20(Predicted) |
| form | solid |
| color | Light yellow to yellow |
Safety information for Pyrithione
Computed Descriptors for Pyrithione
New Products
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