Pyrithione
- CAS NO.：1121-30-8
- Empirical Formula: C5H5NOS
- Molecular Weight: 127.16
- MDL number: MFCD00059791
- EINECS: 214-328-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-16 07:06:08
What is Pyrithione?
Description
The sodium salt of N-hydroxy-2-pyridinethiones has a germicidal activity againts yeasts and fungi. Sodium omadine is a 40% aqueous solution of sodium pyrithione.
The Uses of Pyrithione
It is used in the metallurgical industry as a component of water-based metalwork fluids, of aceto-polyvinyl lattices, water-based printer's ink, lubrieant for synthetie fibers and anti-dandruff shampoos. A case was reported in a metallurgie worker.
Definition
ChEBI: A pyridinethione that is pyridine-2(1H)-thione in which the hydrogen attached to the nitrogen is replaced by a hydroxy group. It is a Zn2+ ionophore; the zinc salt is used as an antifungal and antibacterial agent.
Synthesis Reference(s)
Journal of the American Chemical Society, 72, p. 4362, 1950 DOI: 10.1021/ja01166a008
Properties of Pyrithione
| Melting point: | 68°C |
| Boiling point: | 253.8±23.0 °C(Predicted) |
| Density | 1.255 (estimate) |
| refractive index | 1.5480 (estimate) |
| storage temp. | 2-8°C |
| solubility | DMSO: 125 mg/mL (983.01 mM) |
| pka | 4.70±0.20(Predicted) |
| form | solid |
| color | Light yellow to yellow |
Safety information for Pyrithione
Computed Descriptors for Pyrithione
New Products
2-(2-Chlorophenyl)glycine Propiolic Acid 1-(3-Hydroxy-4-methoxyphenyl)-2-nitroethene (±)-amino(2-fluorophenyl)acetic acid trans-3-Benzyloxy-4-methoxy-beta-nitrostyrene 1-Pentadecanol 2,4-Dihydroxybenzaldehyde Dipropyl disulfide Pyrrolo[1,2-a]pyrimidine-6-carboxylic acid, 4,6,7,8-tetrahydro-4-oxo-, sodium salt (1:1), (6S) Obidoxime hydrochloride API 4 pentyn 1 ol N-Vinylformamide Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 2-Butyn-1-oL N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine Pirtobrutinib intd. 2-Pentyn-1-oL 4-NitrobenzotrifluorideRelated products of tetrahydrofuran
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