POBN
Synonym(s):N-(4-Pyridylmethylene)-tert-butylamine N,N′-dioxide;N-tert-Butyl-α-(4-pyridyl)nitrone N′-oxide;POBN
- CAS NO.：66893-81-0
- Empirical Formula: C10H14N2O2
- Molecular Weight: 194.23
- MDL number: MFCD00041022
- EINECS: 266-512-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:57:00
What is POBN?
Chemical properties
white to pale yellow crystalline powder
The Uses of POBN
Spin trap reagent used to measure ethanol oxidation to 1-hydroxyethyl radical (HER) which can bind to protein. Has also been used in studies of DNA methylation, iron-mediated polyunsaturated fatty acid peroxidation, and free-radical formation by Alzheimer β-amyloid peptide. The formation of hydroxyl radical in chondrocytes and cartilage has been detected using POBN.
The Uses of POBN
POBN is a cell permeable hydrophilic spin trap for in vitro studies. It is a water soluble analog of PBN with low paramagnetic impurities and does not require any further purification. POBN has also also been used in studies of DNA methylation, iron-mediated polyunsaturated fatty acid peroxidation, and free-radical formation by Alzheimer β-amyloid peptide.
What are the applications of Application
POBN is a cell permeable hydrophilic spin trap
Properties of POBN
| Melting point: | 183-185 °C(lit.) |
| Boiling point: | 330.68°C (rough estimate) |
| Density | 1.1444 (rough estimate) |
| refractive index | 1.5000 (estimate) |
| storage temp. | room temp |
| solubility | water: soluble10mg/mL, clear, colorless to faintly yellow |
| form | White to off-white or colorless crystalline solid. |
| pka | 0.76±0.53(Predicted) |
| color | White to Light yellow |
| BRN | 1453764 |
Safety information for POBN
Computed Descriptors for POBN
New Products
1-(4-methoxyphenyl)-4-(4-Nitrophenyl)Piperazine (IT-1) 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-One Dibenzo[b,f][1,4]thiazepin-11(10H)-one Cis-Tosylate Dibenzoyl-L-tartaric acid Anhydrous (Resolution Reagent) 1-Benzhydrylazetane-3-carbonitrile 8-oxa-1,3-diazaspiro[4.5]decane-2,4-dione (±)-amino(2-fluorophenyl)acetic acid 2-(2-Chlorophenyl)glycine AMINO-(3-CHLORO-PHENYL)-ACETIC ACID 2'-Fluoroacetophenone METHANOL-D1(OD) N-ETHYL-D5-AMINE HYDROCHLORIDE BENZOIC ACID-D CHLOROFORM-D BENZENE-D6 TOLUENE-D3 2-Hydroxybutanenitrile 1-Benzylindolin-2-one Ethyl 2-bromo-3-oxobutanoate 4-(3-chloropropyl)morpholine 1-Benzylindoline-2,3-dione 3-Oxocyclobutanecarboxylic acid 1-(3-Chlorophenyl)piperazine hydrochlorideRelated products of tetrahydrofuran
You may like
-
N-tert-Butyl-α-(4-pyridyl-1-oxide)nitrone CAS 66893-81-0View Details
66893-81-0 -
Pobn 95% CAS 66893-81-0View Details
66893-81-0 -
α-(4-Pyridyl N-oxide)-N-tert-butylnitrone CAS 66893-81-0View Details
66893-81-0 -
α-(4-Pyridyl N-oxide)-N-tert-butylnitrone CAS 66893-81-0View Details
66893-81-0 -
5-Bromo-2-chloro- benzoic acid 21739-92-4 98%View Details
21739-92-4 -
52092-43-0 2-Bromo-4-nitropyridine-N-oxide 98%View Details
52092-43-0 -
1-Methylpiperidine-4-thiol 1072-99-7 98%View Details
1072-99-7 -
68886-07-7 98%View Details
68886-07-7