PIPES sesquisodium salt
Synonym(s):1,4-Piperazinediethanesulfonic acid sesquisodium salt;Piperazine-1,4-bis(2-ethanesulfonic acid) sesquisodium salt
- CAS NO.：100037-69-2
- Empirical Formula: C16H33N4Na3O12S4
- Molecular Weight: 670.68
- MDL number: MFCD00066393
- EINECS: 600-018-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:24:53
What is PIPES sesquisodium salt?
Description
PIPES sesquisodium salt is frequently used as a buffering agent in biochemistry. It is an ethanesulfonic acid buffer developed by Good et al. in the 1960s. PIPES has a pKa near the physiological pH which makes it useful in cell culture work. It has been documented to minimize lipid loss when buffering glutaraldehyde histology in plant and animal tissues.
Chemical properties
White powder
The Uses of PIPES sesquisodium salt
PIPES sesquisodium salt is a buffering agent used in biochemistry and molecular biology. It is also a zwitterionic, piperazinic buffer that is useful for a pH range of 6.1 – 7.5.
What are the applications of Application
PIPES, Sesquisodium Salt is PIPES Sesquisodium Salt, is a commonly utilized buffering agent
Properties of PIPES sesquisodium salt
| Melting point: | 300 °C |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | H2O: 0.5 g/mL, clear, colorless |
| pka | 6.8(at 25℃) |
| PH Range | 6.1 - 7.5 |
| Water Solubility | soluble |
| InChI | InChI=1S/2C8H18N2O6S2.3Na/c2*11-17(12,13)7-5-9-1-2-10(4-3-9)6-8-18(14,15)16;;;/h2*1-8H2,(H,11,12,13)(H,14,15,16);;;/q;;3*+1/p-3 |
Safety information for PIPES sesquisodium salt
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for PIPES sesquisodium salt
| InChIKey | FPDACHMSOMILQI-UHFFFAOYSA-K |
| SMILES | S(=O)(=O)(O)CCN1CCN(CCS(=O)(=O)[O-])CC1.S([O-])(=O)(=O)CCN1CCN(CCS([O-])(=O)=O)CC1.[Na+].[Na+].[Na+] |
New Products
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![sodium 2-[(2-aminoethyl)amino]ethanesulphonate](https://img.chemicalbook.in/CAS/GIF/34730-59-1.gif)
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