Disodium piperazine-1,4-diethanesulphonate
Synonym(s):1,4-Piperazinediethanesulfonic acid disodium salt;Piperazine-1,4-bis(2-ethanesulfonic acid) disodium salt;PIPES disodium salt
- CAS NO.：76836-02-7
- Empirical Formula: C8H16N2Na2O6S2
- Molecular Weight: 346.33
- MDL number: MFCD00064349
- EINECS: 278-562-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:24:35
What is Disodium piperazine-1,4-diethanesulphonate?
Chemical properties
White powder
The Uses of Disodium piperazine-1,4-diethanesulphonate
Biological buffer.
The Uses of Disodium piperazine-1,4-diethanesulphonate
PIPES Disodium is the sodium salt form of PIPES and is a biological buffer often referred to as a “Good′s” buffer. The pKa of PIPES is 6.8 which makes it ideal for biological applications at physiological conditions. PIPES Disodium is considered to be non-toxic to culture cell lines, highly water soluble and provides high-solution clarity.
PIPES Disodium can be used in a wide array of biological applications including as a component in media formulations. Specific applications include buffers for cell culture and diagnostic reagent production.
What are the applications of Application
PIPES disodium salt is piperazine-N,N′-bis(2-ethanesulfonic acid), a buffering agent used in biological applications
Definition
ChEBI: An organic salt, being the disodium salt of 2,2'-piperazine-1,4-diylbisethanesulfonic acid (PIPES), a buffering agent.
Flammability and Explosibility
Not classified
Purification Methods
It crystallises from water and EtOH. [Beilstein 23/2 V 380.]
Properties of Disodium piperazine-1,4-diethanesulphonate
| Density | 1.72[at 20℃] |
| vapor pressure | 0Pa at 20℃ |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | H2O: 0.5 g/mL, clear, colorless |
| form | Powder or Crystalline Powder |
| color | White |
| pka | 6.8(at 25℃) |
| PH Range | 6.1 - 7.5 |
| Water Solubility | 855g/L at 19.8℃ |
| Merck | 14,7479 |
| BRN | 9453872 |
| CAS DataBase Reference | 76836-02-7(CAS DataBase Reference) |
| EPA Substance Registry System | 1,4-Piperazinediethanesulfonic acid, disodium salt (76836-02-7) |
Safety information for Disodium piperazine-1,4-diethanesulphonate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Disodium piperazine-1,4-diethanesulphonate
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