Piperazine-N,N'-bis-(2-ethanesulphonic acid) dipotassium salt
Synonym(s):1,4-Piperazinediethanesulfonic acid dipotassium salt;Piperazine-1,4-bis(2-ethanesulfonic acid) dipotassium salt
- CAS NO.：108321-27-3
- Empirical Formula: C8H19KN2O6S2
- Molecular Weight: 342.47
- MDL number: MFCD00069751
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:13:13
What is Piperazine-N,N'-bis-(2-ethanesulphonic acid) dipotassium salt?
Chemical properties
White crystalline powder
The Uses of Piperazine-N,N'-bis-(2-ethanesulphonic acid) dipotassium salt
PIPES (1,4-Piperazinediethanesulfonic acid) dipotassium salt has been used as buffer for fluorescence polarization microscopy studies of kinesin-microtubule binding. It is suitable for use as a component of PHEM buffer ([K-PIPES], HEPES, EGTA, and MgSO4) used during rinsing and blocking steps in immunofluorescence imaging of HeLa cells. It is also suitable for use as buffer for purification of tubulin.
What are the applications of Application
PIPES dipotassium salt is Piperazine-1,4-bis(2-ethanesulfonic acid) dipotassium salt
General Description
PIPES (1,4-Piperazinediethanesulfonic acid) is a zwitterionic buffer. It is a stable buffer and is used majorly in fixation solutions. PIPES is inert towards enzymatic and non-enzymatic reactions. However, it generates artefacts in transmission electron microscope imaging.
Properties of Piperazine-N,N'-bis-(2-ethanesulphonic acid) dipotassium salt
| storage temp. | Store at RT. |
| solubility | H2O: 0.5 g/mL, clear, colorless |
| pka | 6.8(at 25℃) |
| PH Range | 6.1 - 7.5 |
| CAS DataBase Reference | 108321-27-3(CAS DataBase Reference) |
| EPA Substance Registry System | 1,4-Piperazinediethanesulfonic acid, dipotassium salt (108321-27-3) |
Safety information for Piperazine-N,N'-bis-(2-ethanesulphonic acid) dipotassium salt
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. |
Computed Descriptors for Piperazine-N,N'-bis-(2-ethanesulphonic acid) dipotassium salt
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