PINOSYLVIN

Synonym(s):(E)-3,5-Stilbenediol;(E)-5-(2-Phenylethenyl)-1,3-benzenediol;trans-3,5-Dihydroxystilbene;5-Styrylresorcinol;Pinosylvine

CAS NO.：22139-77-1
Empirical Formula: C14H12O2
Molecular Weight: 212.24
MDL number: MFCD00210544
EINECS: 683-184-0
SAFETY DATA SHEET (SDS)
Update Date: 2026-04-22 18:57:36

What is PINOSYLVIN?

Chemical properties

Off-white crystalline powder

The Uses of PINOSYLVIN

Pinosylvin, a pre-infectious stilbenoid toxin, is used to study its properties as a fungitoxin and therapeutic agent. Pinosylvin is used as a representative stilbene to study its biological actions and therapeutic value in processes such as cell survival, apoptosis and cell mobility.

Definition

ChEBI: Pinosylvin is a stilbenol.

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Enzyme inhibitor

This trans-stilbene derivative (FW = 212.25 g/mol; CAS 102-61-4; M.P. = 155.5-156°C; low solubility in water), also known as (E)-3,5-stilbenediol and trans-3,5-dihydroxystilbene and named systematically as 5-[(E)-2- phenylethenyl]benzene-1,3-diol, occurs naturally in the hardwood of pine and other woody plants. Pinosylvin exxhibits micromolar Ki values for specific isozymes of stilbene synthase and chalcone synthase. Target(s): chalcone synthase; stilbene synthase; tyrosinase, or monophenol monooxygenase.

Properties of PINOSYLVIN

Melting point:	153-157 °C
Boiling point:	312.08°C (rough estimate)
Density	1.1035 (rough estimate)
refractive index	1.6000 (estimate)
storage temp.	2-8°C
solubility	DMF: 10mg/mL; DMF:PBS (pH 7.2) (1:50): 0.01mg/mL; DMSO: 10mg/mL; Ethanol: 20mg/mL; Ethanol:PBS (pH 7.2) (1:50): 0.01mg/mL
form	A solid
pka	9.34±0.10(Predicted)
color	White to off-white
BRN	1870942
InChI	InChI=1S/C14H12O2/c15-13-8-12(9-14(16)10-13)7-6-11-4-2-1-3-5-11/h1-10,15-16H/b7-6+

Safety information for PINOSYLVIN

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07 Environment GHS09
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H400:Hazardous to the aquatic environment, acute hazard
Precautionary Statement Codes	P273:Avoid release to the environment. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.