PAF (C18)
Synonym(s):1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine
- CAS NO.：74389-69-8
- Empirical Formula: C28H58NO7P
- Molecular Weight: 551.74
- MDL number: MFCD00063528
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-11 19:39:08
What is PAF (C18)?
Chemical properties
white solid
The Uses of PAF (C18)
C18-02:0 PC or 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine is suitable as a substrate for enzymatic lipoprotein-associated phospholipase A2 (Lp-PLA2) activity assay.
The Uses of PAF (C18)
C18-02:0 PC or 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine may be used as a substrate in enzymatic lipoprotein-associated phospholipase A2 (Lp-PLA2) activity assay.
What are the applications of Application
PAF C-18 is a naturally occurring phospholipid involved in inflammation and other physiological processes
Definition
ChEBI: 2-acyl-1-alkyl-sn-glycero-3-phosphocholine betaine in which the 1-alkyl and 2-acyl groups are specified as octacdecyl and acetyl respectively
General Description
C18-02:0 PC, also known as 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine (C18∶0-PAF), is a platelet-activating factor lipid. It belongs to a class of natural PAFs and is produced in basophil leucocytes, macrophages, polymorphonuclear neutrophils and monocytes and platelets.
Biochem/physiol Actions
C18-02:0 PC or 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine (C18-PAF), a platelet-activating factor (PAF) facilitates platelet aggregation and secretion. It also plays a key role in inflammation and anaphylaxis. C18-PAF exhibits neurotoxic effects by initiating caspase-independent death in PAF receptor-deficient neurons.
Properties of PAF (C18)
| storage temp. | -20°C |
| solubility | chloroform: 10 mg/mL |
Safety information for PAF (C18)
Computed Descriptors for PAF (C18)
New Products
3-AMINO-3-(2-FLUORO-PHENYL)-PROPIONIC ACID Pentadecanoic acid Hendecanoic acid 2-AMINO-3-METHYLQUINOLINE HYDROCHLORIDE 3-Hydroxypropionitrile DL-3-Amino-3-(2-methoxyphenyl)propionic acid 5-Bromo-2-Fluoropyridine 2,3-Diamino-5-Chloropyridine 2-Amino-3-Hydroxypyridine 2,6-Diamino Pyridine 4-Amino-2-Chloropyridine 2-Hydroxy-4-Picoline 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 4-Bromo-3-(ethoxymethyl)benzoic acid 2,4-Dichloro-5-methoxyaniline 4,6-Dichloro-2-(propylthio)pyrimidin-5-amine N2-Isobutyryl-2'-O-methylguanosine 2-chloro-5-methylpyridin-4-amine 4-Bromobenzaldehyde 2-Chloro-6-nitro benzothiazole 2-Amino-4-phenyl-thiazole 4-Chloro-2-methyl quinoline 2-(Chloromethyl) quinazolin-4(3H)-one 5-Phenyl-[1,3,4]-thiadiazol-2-amineRelated products of tetrahydrofuran
![SN-GLYCERO-3-PHOSPHOCHOLINE, 2-PALMITOYL-1-O-HEXA/OCTADECYL, [1,2-3H]](https://img.chemicalbook.in/StructureFile/ChemBookStructure4/GIF/CB4324029.gif)
![1-OCTADECANOYL-2-[(CIS,CIS,CIS,CIS)-5,8,11,14-EICOSATETRAENOYL]-SN-GLYCERO-3-PHOSPHOCHOLINE](https://img.chemicalbook.in/CAS/GIF/35418-59-8.gif)
![1-OCTADECANOYL-2-[CIS-9-OCTADECENOYL]-SN-GLYCERO-3-PHOSPHOCHOLINE](https://img.chemicalbook.in/CAS/GIF/56421-10-4.gif)
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