NEUROTENSIN
- CAS NO.：55508-42-4
- Empirical Formula: C78H121N21O20
- Molecular Weight: 1672.95
- MDL number: MFCD00076678
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 17:34:39
What is NEUROTENSIN?
Definition
ChEBI: Neurotensin is a 13 amino acid peptide hormone which is found in the central nervous system and the gastrointestinal tract. It behaves as a neurotransmitter in the brain, as a hormone in the gut, and also as a neuromodulator. It is implicated in the pathophysiology of several CNS disorders (including schizophrenia, Parkinson's disease, drug abuse, pain, cancer, inflammation, eating disorders and central control of blood pressure) due to its association with a wide variety of neurotransmitter systems such as dopaminergic, sertonergic, glutamatergic, GABAergic, and cholinergic systems. It has a role as a human metabolite, a mitogen, a neurotransmitter and a vulnerary. It is a conjugate base of a neurotensin(1+).
General Description
Neurotensin is a 13-amino-acid peptide, first isolated frombovine hypothalamus. It has now been identified in the intestinaltract. The ileal mucosa contains 90% of the total neurotensinof the body. It is implicated as a releasing factor forseveral adenohypophyseal hormones. It causes vasodilatation,increases vascular permeability, and increases gastrinsecretion. It decreases secretion of gastric acid and secretin.
Properties of NEUROTENSIN
| Density | 1.46±0.1 g/cm3(Predicted) |
| storage temp. | -15°C
|
| pka | 3.41±0.10(Predicted) |
Safety information for NEUROTENSIN
Computed Descriptors for NEUROTENSIN
New Products
Cyclopentane-1,2-dione 2,6-Dibromoaniline 5-Hydroxy-3,9-dimethyl-7H-benzo[c]fluoren-7-one Methyl 4-(acetyloxy)-6-methoxy-1-(4-methoxyphenyl)-2naphthalenecarboxylate 4-Hydroxy-6,7-dimethoxy-1-phenyl-2naphthalenecarboxylic acid (3,5-Dibromophenyl)[4-(trifluoromethyl)phenyl]methanone (4-butoxyphenyl)(4-fluorophenyl)methanone (4-Bromophenyl)(3,4-dimethoxyphenyl)methanone Cefuroxime EP Impurity-A N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity Benzyl-N,4-dimethylpiperidine-3- amine dihydrochloride 3-(4-phenoxyphenyl)-1H- pyrazolo[3,4- d]pyrimidin-4- amine 4-Ethyl-4-hydroxy-1,4,7,8-tetrahydro-3H,10H-spiro[pyrano[3,4-f]indolizine-6,2'-[1,3]dioxolane]-3,10-dione (E)-N'-(2-cyano-4-nitrophenyl)- N,N-dimethylformimidamide N-(8-Amino-6-fluoro-5-methyl-1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)acetamide 5-bromopyridin-2-amine 2-Chloro Benzylcyanide 3-chlorobenzyl cyanide 3,4 Diethoxy Benzylcyanide 3,4 Dimethoxy BenzylcyanideRelated products of tetrahydrofuran
![[LYS8,9]-NEUROTENSIN (8-13),(LYS8,LYS9)-NEUROTENSIN (8-13)](https://img.chemicalbook.in/CAS/GIF/139026-64-5.gif)
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