Neurotensin (8-13)
- CAS NO.：60482-95-3
- Empirical Formula: C38H64N12O8
- Molecular Weight: 816.99
- MDL number: MFCD00076686
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:48:19
What is Neurotensin (8-13)?
Biological Activity
Neurotensin (8-13) is the active fragment of neurotensin, Neurotensin (8-13) reduces cell surface NT1 receptor (NTR1) density.
in vitro
Receptor internalization induced by Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density. The receptor downregulation in response to high extracellular concentrations of the peptide has been described for Neurotensin (NT ) in HT-29 cells and in rat primary cultured neurons. Reappearance of the receptors on the cell surface is also different.
Properties of Neurotensin (8-13)
| Density | 1.40±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
| form | Solid |
| pka | 3.41±0.10(Predicted) |
| color | White to off-white |
| Water Solubility | Water: 50 mg/mL (61.20 mM) |
Safety information for Neurotensin (8-13)
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Neurotensin (8-13)
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