DMT-dG(dmf) Phosphoramidite
Synonym(s):DMT-dG(dmf) Amidite;N-[(dimethylamino)methylene]-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyguanosine, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite];N2-Dimethylformamidine-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine-3′-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite]
- CAS NO.：330628-04-1
- Empirical Formula: C43H53N8O7P
- Molecular Weight: 824.9
- MDL number: MFCD09842106
- EINECS: 2017-001-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:21:15
What is DMT-dG(dmf) Phosphoramidite?
Chemical properties
White or off-white power
The Uses of DMT-dG(dmf) Phosphoramidite
Dmf-dG-CE phosphoramidite is a nucleotide and guanosine (G837895) derivative used in the preparation of synthetic RNA fragments, and other macromolecules such as micellar thrombin-binding aptamers as anticoagulants.
Definition
5'-O-DMT-2'-Deoxyguanosine(DMF)-CE Phosphoramidite, or DMT-dG(dmf) Phosphoramidite, is a nucleoside amidite analog comprised of 2'-deoxy-N2,5'-O-dimethoxytrityl guanosine (DMF) and 5'-O-dimethoxytrityl cytidine monophosphate (DMT).
Properties of DMT-dG(dmf) Phosphoramidite
| Boiling point: | 876.3±75.0 °C(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | DMSO : 100 mg/mL (121.23 mM; Need ultrasonic) |
| pka | 3.80±0.20(Predicted) |
| form | powder |
| color | white to off-white |
Safety information for DMT-dG(dmf) Phosphoramidite
Computed Descriptors for DMT-dG(dmf) Phosphoramidite
| InChIKey | YRQAXTCBMPFGAN-UNHDIWNRSA-N |
| SMILES | C12N=C(/N=C/N(C)C)NC(=O)C=1N=CN2[C@H]1C[C@@H]([C@@H](COC(C2C=CC=CC=2)(C2C=CC(OC)=CC=2)C2=CC=C(C=C2)OC)O1)OP(OCCC#N)N(C(C)C)C(C)C |&1:15,17,18,r| |
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![5'-Dimethoxytrityl-3'-deoxythymidine 2'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite](https://img.chemicalbook.in/CAS/GIF/98796-51-1.gif)
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