DMT-dG(ib) Phosphoramidite
Synonym(s):DMT-dG(ib) amidite;DMT-dG(ib) Phosphoramidite;Guanosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-N-(2-methyl-1-oxopropyl)-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite];N-(2-methyl-1-oxopropyl)-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyguanosine, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite];N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine-3′-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite]
- CAS NO.：93183-15-4
- Empirical Formula: C44H54N7O8P
- Molecular Weight: 839.92
- MDL number: MFCD00055147
- EINECS: 685-519-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:24:38
What is DMT-dG(ib) Phosphoramidite?
The Uses of DMT-dG(ib) Phosphoramidite
2’-Deoxy-5’-O-DMT-N2-isobutyrylguanosine 3’-CE Phosphoramidite is used to prepare antisense oligonucleotides containing conformationally constrained methoxyaminomethylene and aminooxymethylene and aminomethylene bridged nucleoside analogs.
Definition
5'-O-DMT-N2-Isobutyryl-2'-Deoxyguanosine-CE Phosphoramidite (DMT-dG(ib) Phosphoramidite) is a nucleoside phosphoramidite that contains an isobutyryl group, and it can be used in the synthesis of oligonucleotides.
Storage
-20°C, stored under nitrogen.
In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Properties of DMT-dG(ib) Phosphoramidite
| Density | 1.22 at 20℃ |
| vapor pressure | 0-0Pa at 20-50℃ |
| storage temp. | Sealed in dry,2-8°C |
| solubility | soluble, clear |
| form | powder or granules |
| pka | 9.16±0.20(Predicted) |
| color | white to off-white |
Safety information for DMT-dG(ib) Phosphoramidite
Computed Descriptors for DMT-dG(ib) Phosphoramidite
| InChIKey | FDRMKYVTIFSDPR-MMROLVBFSA-N |
| SMILES | C(OC[C@H]1O[C@@H](N2C=NC3C(=O)NC(NC(=O)C(C)C)=NC2=3)C[C@@H]1OP(OCCC#N)N(C(C)C)C(C)C)(C1=CC=CC=C1)(C1=CC=C(OC)C=C1)C1=CC=C(OC)C=C1 |&1:3,5,23,r| |
DMT-dG(ib) Phosphoramidite manufacturer
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product: 93183-15-4 98%
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