Melagatran
- CAS NO.：159776-70-2
- Empirical Formula: C22H31N5O4
- Molecular Weight: 429.51
- MDL number: MFCD00945676
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-14 16:49:18
What is Melagatran?
Chemical properties
White Solid
The Uses of Melagatran
Synthetic thrombin inhibitor. Thrombin mutant anticoagulant antagonist. Antithrombotic
The Uses of Melagatran
Synthetic thrombin inhibitor. Thrombin mutant anticoagulant antagonist. Antithrombotic.
What are the applications of Application
Melagatran is A thrombin mutant anticoagulant antagonist.
Definition
ChEBI: Melagatran is a member of the class of azetidines that is (2S)-azetidine 2-carboxylic acid in which the carboxylic acid has been converted to the amide corresponding to formal condensation with 4-(aminomethyl)benzenecarboximidamide and in which the hydrogen attached to the azetidine nitrogen is replaced by a (2R)-2-cyclohexyl-2-[(carboxymethyl)amino]acetyl group. It has a role as an anticoagulant, an EC 3.4.21.5 (thrombin) inhibitor and a serine protease inhibitor. It is a carboxamidine, a dicarboxylic acid monoamide, a non-proteinogenic alpha-amino acid, a secondary amino compound and a member of azetidines.
Properties of Melagatran
| Melting point: | 198-200°C |
| Density | 1.41±0.1 g/cm3(Predicted) |
| storage temp. | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 2.12±0.10(Predicted) |
| color | White to Off-White |
| Stability: | Hygroscopic |
Safety information for Melagatran
Computed Descriptors for Melagatran
New Products
2-(2-Chlorophenyl)glycine Propiolic Acid 1-(3-Hydroxy-4-methoxyphenyl)-2-nitroethene (±)-amino(2-fluorophenyl)acetic acid trans-3-Benzyloxy-4-methoxy-beta-nitrostyrene 1-Pentadecanol 2,4-Dihydroxybenzaldehyde Dipropyl disulfide Pyrrolo[1,2-a]pyrimidine-6-carboxylic acid, 4,6,7,8-tetrahydro-4-oxo-, sodium salt (1:1), (6S) Obidoxime hydrochloride API 4 pentyn 1 ol N-Vinylformamide Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 2-Butyn-1-oL N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine Pirtobrutinib intd. 2-Pentyn-1-oL 4-NitrobenzotrifluorideRelated products of tetrahydrofuran
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