JWH 018 adamantyl carboxamide

CAS NO.：1345973-50-3
Empirical Formula: C24H32N2O
Molecular Weight: 364.52
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-15 10:43:29

What is JWH 018 adamantyl carboxamide?

Description

JWH 018 is a synthetic cannabinoid (CB) which potently activates both the central CB₁ and peripheral CB₂ receptors (K_i = 9.0 and 2.94 nM, respectively). This cannabimimetic compound has frequently been found in herbal blends. Structurally, JWH 018 is an alkylindole joined to a naphthyl group by methanone. JWH 018 adamantyl carboxamide is a structural analog of JWH 018 where the naphthalenyl-methanone portion has been replaced by adamantyl carboxamide. While the physiological properties of this compound are not known, quinolones with adamantyl carboxamide moieties display high affinity for the CB₂ receptor but greatly reduced affinity for the CB₁ receptor. This product is intended for research and forensic applications.

The Uses of JWH 018 adamantyl carboxamide

APICA, is a synthetic cannabinoid (CB) which potently activates both the central CB1 and peripheral CB2 receptors (Ki = 9.0 and 2.94 nM, respectively). Synthetic Cannabinoids

Properties of JWH 018 adamantyl carboxamide

Boiling point:	573.1±23.0 °C(Predicted)
Density	1.24±0.1 g/cm3(Predicted)
solubility	DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 1 mg/ml
form	A neat solid
pka	14.62±0.20(Predicted)

Safety information for JWH 018 adamantyl carboxamide

Computed Descriptors for JWH 018 adamantyl carboxamide

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