halopredone
- CAS NO.：57781-15-4
- Empirical Formula: C21H25BrF2O5
- Molecular Weight: 475.32
- MDL number: MFCD09837985
- EINECS: 260-953-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2022-12-21 16:56:50
What is halopredone?
Originator
Topicon,Pierrel,Italy,1983
The Uses of halopredone
Anti-inflammatory (topical).
Manufacturing Process
100 ml of a 70% hydrofluoric acid aqueous solution were cooled to -10°C in a polyethylene flask equipped with electromagnetic stirrer. 10 g of 2-bromo-6β- fluoro-17α,21-dihydroxy-9β, 11β-oxido-pregna-1,4-diene-3,20-dione-17,21- diacetate were added under stirring during 15 minutes. After 0.5 hour the reaction mixture was precipitated in water and ammonia. The solid was collected by filtration, washed with water and dried to a constant weight, giving about 9.5 g of 2-bromo-6β,9α-difluoro-11β,17α,21 -trihydroxypregna- 1,4-diene-3,20-dione-17,21-diacetate.
Therapeutic Function
Topical antiinflammatory
Properties of halopredone
| Boiling point: | 611.8±55.0 °C(Predicted) |
| Density | 1.59±0.1 g/cm3(Predicted) |
| pka | 11.91±0.70(Predicted) |
Safety information for halopredone
Computed Descriptors for halopredone
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