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HomeProduct name listDAPH

DAPH

  • CAS NO.:145915-58-8
  • Empirical Formula: C20H15N3O2
  • Molecular Weight: 329.35
  • MDL number: MFCD00236442
  • EINECS: 406-050-3
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2025-12-23 21:30:31
DAPH Structural

What is DAPH?

The Uses of DAPH

CGP 52411 is a protein-tyrosine kinase inhibitor with selectivity for the epidermal growth factor receptor signal transduction pathway and potent in vivo antitmuor activity. It may offer therapeutic agents for the treatment of hyperproliferative diseases.

What are the applications of Application

DAPH is an inhibitor of EGFR kinase 3

Definition

ChEBI: 4,5-dianilinophthalimide is phthalimide substituted at the 4- and 5-positions by anilino groups. It has a role as a tyrosine kinase inhibitor and a geroprotector.

Biochem/physiol Actions

DAPH is an inhibitor of Aβ fibril formation; Protein tyrosine kinase inhibitor, specific for EGFR.

Properties of DAPH

Melting point: 199-202℃
Density  1.374
storage temp.  2-8°C
solubility  DMSO: ~30 mg/mL
form  solid
pka 9.06±0.20(Predicted)
color  orange

Safety information for DAPH

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H303:Acute toxicity,oral
Precautionary Statement Codes P312:Call a POISON CENTER or doctor/physician if you feel unwell.

Computed Descriptors for DAPH

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