METHYL 2,5-DIHYDROXYCINNAMATE
- CAS NO.：63177-57-1
- Empirical Formula: C10H10O4
- Molecular Weight: 194.18
- MDL number: MFCD00132932
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-12-08 19:11:55
What is METHYL 2,5-DIHYDROXYCINNAMATE?
Chemical properties
Yellow-Brown Crystalline Powder
The Uses of METHYL 2,5-DIHYDROXYCINNAMATE
A stable Erbstatin analogue that inhibits tyrosine kinase. Shown to delay the S-phase induction by epidermal growth factor in quiescent normal rat kidney cells, without affecting the total amount of DNA synthesis
The Uses of METHYL 2,5-DIHYDROXYCINNAMATE
An inhibitor of the EGF receptor associated tyrosine kinase
What are the applications of Application
Erbstatin Analog is a stable inhibitor of EGFR tyrosine kinase
Definition
ChEBI: 2,5-dihydroxycinnamic acid methyl ester is a cinnamate ester that is the methyl ester of 2,5-dihydroxycinnamic acid. It has a role as a human urinary metabolite, a plant metabolite, a geroprotector and an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor. It is a cinnamate ester, a member of hydroquinones and a methyl ester.
Properties of METHYL 2,5-DIHYDROXYCINNAMATE
| Melting point: | 178-180°C |
| Density | 1.318±0.06 g/cm3 (20 ºC 760 Torr) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | 0.1 M NaOH: soluble |
| form | crystalline |
| color | yellow |
| Water Solubility | Soluble in methanol or 0.1M NaOH. Insoluble in water |
| CAS DataBase Reference | 63177-57-1(CAS DataBase Reference) |
Safety information for METHYL 2,5-DIHYDROXYCINNAMATE
| Signal word | Warning |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H311:Acute toxicity,dermal H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H331:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for METHYL 2,5-DIHYDROXYCINNAMATE
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