DAGO ACETATE SALT
Synonym(s):DAGO;DAMGO;Tyr-D -Ala-Gly-N-methyl-Phe-Gly-ol
- CAS NO.：100929-53-1
- Empirical Formula: C28H39N5O8
- Molecular Weight: 573.64
- MDL number: MFCD00133215
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:23:25
What is DAGO ACETATE SALT?
The Uses of DAGO ACETATE SALT
Mu-opioid receptor-specific enkephalin analog
The Uses of DAGO ACETATE SALT
[D-Ala2, N-Me-Phe4, Gly5-ol]-Enkephalin acetate salt or DAMGO has been used:
- for use as a positive control in the assay of G-protein activation with μ-opioid receptor, to assay the inhibition of cAMP inhibition by DAMGO
- for the determination of the suppression of contraction by opioid receptors
- to determine whether the peripheral application of DAMGO suppresses the hypertonic saline (HS)-induced masseter nociception in slightly anaesthetized rats
General Description
[D-Ala2, N-Me-Phe4, Gly5-ol]-Enkephalin acetate salt or DAMGO is a full agonist of the μ-opioid receptor. μ-opioid receptor is encoded by the OPRM1 gene, which has a predominant expression in reward-processing areas of brain. It acts as a receptor for endogenous opioids such as β-endorphin, encephalin, as well as foreign opioids such as morphine, heroin, and methadone.
Biochem/physiol Actions
Enkephalin analog that is a selective agonist at μ-opioid receptors.
Properties of DAGO ACETATE SALT
| storage temp. | −20°C |
| form | Powder |
| EPA Substance Registry System | L-Tyrosyl-D-alanylglycyl-N-(2-hydroxyethyl)-N-.alpha.-methyl-L-phenylalaninamide monoacetate (salt) (100929-53-1) |
Safety information for DAGO ACETATE SALT
Computed Descriptors for DAGO ACETATE SALT
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