Amodiaquin dihydrochloride dihydrate
Synonym(s):4-([7-Chloro-4-quinolinyl]amino)-2-([diethylamino]methyl)phenol;Amodiaquin dihydrochloride dihydrate
- CAS NO.：6398-98-7
- Empirical Formula: C20H25Cl2N3O2
- Molecular Weight: 410.34
- MDL number: MFCD09260307
- EINECS: 642-210-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-07 16:53:29
What is Amodiaquin dihydrochloride dihydrate?
Chemical properties
Light yellow powder
The Uses of Amodiaquin dihydrochloride dihydrate
antimalarial
The Uses of Amodiaquin dihydrochloride dihydrate
An anti-malarial quinoline derivative that acts as an histamine N-methyltransferase inhibitor
brand name
Camoquin (Parke-Davis).
Biological Activity
Amodiaquine is a potent, non-competitive inhibitor of histamine N-methyl transferase with estimated Ki of 18.6 nM. It is also used as an antimalarial and anti-inflammatory agent.
in vivo
In vivo administration of a small dose amodiaquine dramatically enhanced the effect of histamine on the gastric secretion in dogs. Amodiaquine prevents severe hepatic injury and high lethality in P. acnes-primed and LPS-induced hepatitis mice. Its treatment enhances the elevation of histamine in the liver of P. acnes-primed and LPS-induced hepatitis mice without accompanying tele-methyl histamine elevation.
Properties of Amodiaquin dihydrochloride dihydrate
| RTECS | GO7300100 |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Soluble in DMSO or methanol |
| form | neat |
| form | Solid |
| color | White to Yellow to Orange |
| λmax | 342nm(MeOH)(lit.) |
| Merck | 14,572 |
| Stability: | Hygroscopic |
| CAS DataBase Reference | 6398-98-7(CAS DataBase Reference) |
Safety information for Amodiaquin dihydrochloride dihydrate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P312:Call a POISON CENTER or doctor/physician if you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. |
Computed Descriptors for Amodiaquin dihydrochloride dihydrate
New Products
Cis-Tosylate Dibenzo[b,f][1,4]thiazepin-11(10H)-one Dibenzoyl-L-tartaric acid Anhydrous (Resolution Reagent) 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-One N-BOC-piperidine-4-carboxylic acid 1-Benzhydrylazetane-3-carbonitrile AMINO-(3-CHLORO-PHENYL)-ACETIC ACID 2-(2-Chlorophenyl)glycine (±)-amino(2-fluorophenyl)acetic acid 8-oxa-1,3-diazaspiro[4.5]decane-2,4-dione TRIFLOURO ACETICACID-D METHANE SULFONIC ACID-D4 PHOSPORIC ACID-D3 85 W% IN D2O DEUTERIUM OXIDE FOR NMR TOLUENE-D3 BENZENE-D6 1-Acetyl-4-(4-hydroxyphenyl)piperazine 1-(3-Chlorophenyl)piperazine hydrochlorideRelated products of tetrahydrofuran
You may like
-
Amodiaquine Dihydrochloride Dihydrate CAS 6398-98-7View Details
6398-98-7 -
Amodiaquin diHCl dihydrate 98% CAS 6398-98-7View Details
6398-98-7 -
Amodiaquine hydrochloride CAS 6398-98-7View Details
6398-98-7 -
Amodiaquine HCL API, 25Kg, 98%View Details
6398-98-7 -
Amodiaquine Hcl ApiView Details
86-42-0 -
Amodiaquine HCL APIView Details
86-42-0 -
7292-71-9 AMINO-(3-CHLORO-PHENYL)-ACETIC ACID 98+View Details
7292-71-9 -
2-(2-Chlorophenyl)glycine 98+View Details
88744-36-9
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.