(6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride
Synonym(s):(−)-(S)-5,6,7,8-Tetrahydro-6-(propyl(2-(2-thienyl)ethyl)amino)-1-naphthol hydrochloride;(−)-N 0437;N 0923;Neupro;SPM 962
- CAS NO.：125572-93-2
- Empirical Formula: C19H26ClNOS
- Molecular Weight: 351.93
- MDL number: MFCD00906149
- EINECS: 603-080-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-12-07 19:09:50
What is (6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride?
Chemical properties
White to Off-White Solid
The Uses of (6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride
It is a non-ergot dopamine agonist drug and is indicated for the treatment of Parkinson’s disease.
What are the applications of Application
Rotigotine Hydrochloride is a D2DR and D3DR agonist
Biochem/physiol Actions
Rotigotine is a dopamine receptor agonist with preference for D3 receptors over D2 and D1. As such, it is an effective anti-Parkinsonian agent. Racemic rotigotine is about 50 times as potent as quinpirole, the gold standard D2 agonist.
Storage
room temperature (desiccate)
Properties of (6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride
| Melting point: | 114-117°C |
| Density | 1.2g/cm3 at 20℃ |
| vapor pressure | 0-0Pa at 20-25℃ |
| storage temp. | room temp |
| solubility | Acetone (Slightly, Heated, Sonicated), DMSO (Slightly), Methanol (Slightly) |
| form | solid |
| color | white to off-white |
| Stability: | Hygroscopic |
Safety information for (6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride
Computed Descriptors for (6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride
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