6-Bromonaphthalen-2-amine

CAS NO.：7499-66-3
Empirical Formula: C10H8BrN
Molecular Weight: 222.08
MDL number: MFCD01026466
EINECS: 1308068-626-2
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 05:23:17

What is 6-Bromonaphthalen-2-amine?

The Uses of 6-Bromonaphthalen-2-amine

6-Bromonaphthalen-2-amine is used in the new synthesis of alkylsulphanylnaphthalenes and the synthesis and mesomorphic properties of novel naphthylisothiocyanates.

What are the applications of Application

6-Bromonaphthalen-2-amine can be used to prepare light-emitting diode materials, amine compounds, deuterated aromatic compounds and deuterated compositions thereof.

Synthesis

6-Bromo-2-naphthoic acid (5.07g, 20.19mmol) and triethylamine (4.22mL, 3.07g, 30.3mmol) in dry DMF (155mL) were treated with the diphenylphosphoroyl azide (6.55mL, 8.34g, 30.3mmol) followed by stirring at room temperature for 3h. The solution was then treated with water (2OmL) and warming at 1000C for Ih. The solution was cooled in the flask fitted with a short-path distillation head, and the DMF was removed by distillation under a high vacuum. The solid residue was dissolved in EtOAc and washed with a saturated sodium bicarbonate solution. Filtered through celite, the filtrate was washed with water (3x) and brine. Dried over, filtered, and concentrated under vacuum to give 6-Bromonaphthalen-2-amine as a beige solid (4.48g, 100 percent).

Properties of 6-Bromonaphthalen-2-amine

Melting point:	128 °C
Boiling point:	155-160 °C(Press: 1 Torr)
Density	1.563±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly)
pka	3.66±0.10(Predicted)
color	grey
InChI	InChI=1S/C10H8BrN/c11-9-3-1-8-6-10(12)4-2-7(8)5-9/h1-6H,12H2

Safety information for 6-Bromonaphthalen-2-amine

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.