2-Amino-6-bromopyridine

CAS NO.：19798-81-3
Empirical Formula: C5H5BrN2
Molecular Weight: 173.01
MDL number: MFCD00137843
EINECS: 606-385-7
SAFETY DATA SHEET (SDS)
Update Date: 2025-12-07 19:09:50

What is 2-Amino-6-bromopyridine?

Chemical properties

Slightly yellow to light brown powder

The Uses of 2-Amino-6-bromopyridine

2-Amino-6-bromopyridine is a disubstituted pyridine used as a building block in the preparation of nitrogen containing bicyclic and polycylic compounds.

The Uses of 2-Amino-6-bromopyridine

Employed in an efficient one-pot synthesis of 7-azaindoles. Used in the synthesis of anti-HIV agents.

What are the applications of Application

2-Amino-6-bromopyridine is an important raw material for the synthesis of:
2-amino-6-diethylaminopyridine
2,6-di-(methylamino)-pyridine
3-(6-bromopyridin-2-yl)-2-(2,6-difluorophenyl)-1,3-thiazolidin-4-one
N-(6-bromopyridin-2-yl)dodecylamide
2-bromo-6-iodopyridine
Employed in an efficient one-pot synthesis of 7-azaindoles.
Used in the synthesis of anti-HIV agents.

General Description

2-Amino- 6-bromopyridine has been synthesized from epichlorohydrin.

Properties of 2-Amino-6-bromopyridine

Melting point:	88-91 °C (lit.)
Boiling point:	273.0±20.0 °C(Predicted)
Density	1.710±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Methanol (Very Slightly)
form	Powder
pka	2.73±0.24(Predicted)
color	Slightly yellow to light brown
Water Solubility	Slightly soluble in water.
CAS DataBase Reference	19798-81-3(CAS DataBase Reference)

Safety information for 2-Amino-6-bromopyridine

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.