5-Methylsalicylic acid
Synonym(s):p-Cresotic acid;2-Hydroxy-5-methylbenzoic acid
- CAS NO.：89-56-5
- Empirical Formula: C8H8O3
- Molecular Weight: 152.15
- MDL number: MFCD00002461
- EINECS: 201-918-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 04:22:58
What is 5-Methylsalicylic acid?
Chemical properties
5-Methylsalicylic acid is a white to beige powder that is soluble in basic water and in polar organic solvents. At neutral pH, the acid exists as 5-methylsalicylate Its functional groups include a carboxylic acid and a phenol group. It is one of four isomers of methylsalicylic acid.
The Uses of 5-Methylsalicylic acid
Toxicity is similar to salicylic acid. 5-Methylsalicylic acid is used in manufacturing of dyes.
The Uses of 5-Methylsalicylic acid
5-Methylsalicylic acid was used in generation of o-sulfate conjugates in situ and their analysis by ultra-performance liquid chromatography-time-of-flight mass spectrometry.
Preparation
5-Methylsalicylic acid can be prepared by hydroxylation of 3-methylbenzoic acid.
General Description
5-Methylsalicylic acid exhibits a significant cross-reactivity during fluorescent polarization immunoassay for salicylates in serum.
Purification Methods
Crystallise the acid from H2O. [Beilstein 10 H 227, 10 II 134, 10 III 516, 10 IV 610.]
Properties of 5-Methylsalicylic acid
| Melting point: | 150-154 °C (lit.) |
| Boiling point: | 234.6°C (rough estimate) |
| Density | 1.2143 (rough estimate) |
| refractive index | 1.4945 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| form | Powder |
| pka | pK1:4.08 (25°C) |
| color | White to beige |
| Water Solubility | 21.9g/L(100 ºC) |
| Merck | 14,2582 |
| BRN | 1909076 |
| CAS DataBase Reference | 89-56-5(CAS DataBase Reference) |
| NIST Chemistry Reference | 5-Methylsalicylic acid(89-56-5) |
Safety information for 5-Methylsalicylic acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 5-Methylsalicylic acid
New Products
9-Mesityl-10-methylacridinium perchlorate Sulfapyridine Fmoc-OSu (R)-(-)-2-Amino-1-propanol Cyclobutanone 5-bromo-4-fluoro-2-nitrobenzaldehyde 4 pentyn 1 ol N-Vinylformamide Phenethyl cinnamate Pyrrolo[1,2-a]pyrimidine-6-carboxylic acid, 4,6,7,8-tetrahydro-4-oxo-, sodium salt (1:1), (6S) Ethyl 3-phenylpropanoate β-Bromostyrene Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 5-Bromo-1-Pentyne 1-(2-Methyl-5-nitrophenyl)guanidine Nitrate Methyl trans-4-Aminocyclohexanecarboxylate Hydrochloride N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide 4-Nitrobenzotrifluoride 2-Pentyn-1-oLRelated products of tetrahydrofuran
You may like
-
6-Hydroxy-m-toluic acid 98%View Details
89-56-5 -
5-Methylsalicylic Acid CAS 89-56-5View Details
89-56-5 -
5-Methylsalicylic acid CAS 89-56-5View Details
89-56-5 -
Fmoc-OSu 98+View Details
82911-69-1 -
1191-95-3 Cyclobutanone 98+View Details
1191-95-3 -
213382-45-7 98+View Details
213382-45-7 -
Fmoc-OSu 98+View Details
82911-69-1 -
(R)-(-)-2-Amino-1-propanol 35320-23-1 98+View Details
35320-23-1
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.